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Tdark
TMEM52
Transmembrane protein 52

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310991
  • ENSP00000311122
  • ENSG00000178821
  • ENST00000378602
  • ENSP00000367865
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.8
tissue sample
0.6
transcription factor
0.55
gene perturbation
0.53
tissue
0.49


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 5   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
4
3
4
80.9
influenza A (H1N1)
1
1
0
16.9
36.9
lifestyle measurement
1
1
1
13.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
4
80.9
influenza A (H1N1)
0
16.9
36.9
lifestyle measurement
1
13.7
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 52
709340
Mouse
MGI:1916921
69671
Rat
RGD:2318502
100362283
Dog
transmembrane protein 52
VGNC:53468
607284
Horse
transmembrane protein 52
VGNC:24297
102149877
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 52
Mouse
Rat
Dog
transmembrane protein 52
Horse
transmembrane protein 52
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NDY8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (32)
1 – 10 of 32
GPATCH4
Tdark
Novelty:  1.13040547
Score:  0.696
Data Source:  STRINGDB
SINHCAF
Tdark
Novelty:  0.18692832
Score:  0.693
Data Source:  STRINGDB
STEAP2
Tbio
Family:  Enzyme
Novelty:  0.02727622
Score:  0.681
Data Source:  STRINGDB
CFAP74
Tdark
Novelty:  0.37177561
Score:  0.669
Data Source:  STRINGDB
TMEM120B
Tdark
Novelty:  1.46242586
Score:  0.655
Data Source:  STRINGDB
MMGT1
Tdark
Novelty:  0.20333677
Score:  0.631
Data Source:  STRINGDB
GUCA2A
Tbio
Novelty:  0.00856211
Score:  0.627
Data Source:  STRINGDB
CALML6
Tbio
Novelty:  0.17113396
Score:  0.602
Data Source:  STRINGDB
CLSTN2
Tbio
Novelty:  0.011364
Score:  0.589
Data Source:  STRINGDB
TMEM30B
Tbio
Novelty:  0.26735006
Score:  0.581
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.26

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer