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Tbio
CFAP43
Cilia- and flagella-associated protein 43

Protein Summary
Description
Flagellar protein involved in sperm flagellum axoneme organization and function. This gene encodes a member of the cilia- and flagella-associated protein family. [provided by RefSeq, Sep 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357060
  • ENSP00000349568
  • ENSG00000197748

Symbol
  • C10orf79
  • WDR96
  • WDR96
  • SPGF19
  • C10orf79
  • bA373N18.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
tissue sample
0.57
cell line
0.54
phenotype
0.54
transcription factor
0.54


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.82   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.82   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 43
VGNC:1603
450718
Mouse
MGI:1289258
100048534
Rat
RGD:1560545
365476
Dog
cilia and flagella associated protein 43
VGNC:39162
486877
Cow
cilia and flagella associated protein 43
VGNC:27243
518801
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 43
Mouse
Rat
Dog
cilia and flagella associated protein 43
Cow
cilia and flagella associated protein 43
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NDM7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (18)
1 – 10 of 18
DNAH1
Tbio
Novelty: 0.0369386
Score: 0.629
Data Source: STRINGDB
HPCAL4
Tdark
Novelty: 0.26673582
Score: 0.544
Data Source: STRINGDB
IFT80
Tbio
Novelty: 0.04862973
Score: 0.544
Data Source: STRINGDB
SPATA22
Tbio
Novelty: 0.18061361
Score: 0.531
Data Source: STRINGDB
RSPH1
Tbio
Novelty: 0.02982525
Score: 0.515
Data Source: STRINGDB
DEFB129
Tdark
Novelty: 0.26809608
Score: 0.514
Data Source: STRINGDB
RSPH4A
Tbio
Novelty: 0.07992083
Score: 0.499
Data Source: STRINGDB
GAS8
Tbio
Novelty: 0.03540885
Score: 0.482
Data Source: STRINGDB
SPEF2
Tdark
Novelty: 0.03559091
Score: 0.479
Data Source: STRINGDB
SPAG6
Tbio
Novelty: 0.01327217
Score: 0.476
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.82

PubMed score by year
PubTator Score  1.95

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer