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Tbio
PNMA1
Paraneoplastic antigen Ma1

Protein Summary
Description
This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors. [provided by RefSeq, Feb 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316836
  • ENSP00000318914
  • ENSG00000176903

Symbol
  • MA1
  • MA1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.83
kinase perturbation
0.81
cellular component
0.66
cell line
0.61
transcription factor binding site profile
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.7   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 185   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.7   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 185   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (45)
1 – 10 of 45
MOAP1
Tbio
Novelty: 0.05070263
p_int: 0.999999542
p_ni: 4.27e-7
p_wrong: 3.1e-8
Score: 0.717
Data Source: BioPlex,STRINGDB
PNMA8A
Tdark
Novelty: 0.95674878
p_int: 0.999997546
p_ni: 0.000002427
p_wrong: 2.6e-8
Score: 0.847
Data Source: BioPlex,STRINGDB
REPS1
Tbio
Novelty: 0.08952347
p_int: 0.999941578
p_ni: 0.000051123
p_wrong: 0.000007299
Score: 0.183
Data Source: BioPlex,STRINGDB
MAP7
Tbio
Novelty: 0.01976296
p_int: 0.999904417
p_ni: 0.000009621
p_wrong: 0.000085961
Data Source: BioPlex
ZCCHC12
Tbio
Novelty: 0.16283891
p_int: 0.999458421
p_ni: 8.5e-8
p_wrong: 0.000541494
Score: 0.533
Data Source: BioPlex,STRINGDB
BTBD1
Tbio
Novelty: 0.19772296
p_int: 0.997904903
p_ni: 0.00209347
p_wrong: 0.000001627
Score: 0.19
Data Source: BioPlex,STRINGDB
UBA5
Tbio
Novelty: 0.05089296
p_int: 0.980282461
p_ni: 0.019717539
Score: 0.173
Data Source: BioPlex,STRINGDB
ACTBL2
Tbio
Novelty: 0.18080702
p_int: 0.978577338
p_ni: 0.021422662
Score: 0.226
Data Source: BioPlex,STRINGDB
ACTA2
Tbio
Novelty: 0.00199354
p_int: 0.941786214
p_ni: 0.058213786
Data Source: BioPlex
ACTB
Tbio
Novelty: 0.00006048
p_int: 0.844496275
p_ni: 0.155503725
Data Source: BioPlex
Publication Statistics
PubMed Score  15.70

PubMed score by year
PubTator Score  81.93

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer