You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
GIMAP8
GTPase IMAP family member 8

Protein Summary
Description
Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections. This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307271
  • ENSP00000305107
  • ENSG00000171115

Symbol
  • IAN9
  • IANT
  • IAN6
  • IAN9
  • IANT
  • IAN-9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.73
gene perturbation
0.71
tissue sample
0.68
metabolite
0.45
cell type or tissue
0.44


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 123   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
GTPase, IMAP family member 8
VGNC:4374
472631
Macaque
GTPase, IMAP family member 8
713236
Mouse
MGI:2685303
243374
Rat
RGD:1564570
500112
Dog
GTPase, IMAP family member 8
VGNC:41219
482794
Species
Name
OMA
EggNOG
Inparanoid
Chimp
GTPase, IMAP family member 8
Macaque
GTPase, IMAP family member 8
Mouse
Rat
Dog
GTPase, IMAP family member 8
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8ND71-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (52)
1 – 10 of 52
OAS2
Tbio
Family: Enzyme
Novelty: 0.01673393
p_int: 0.999997076
p_ni: 0.000002918
p_wrong: 6e-9
Score: 0.506
Data Source: BioPlex,STRINGDB
SRP68
Tbio
Novelty: 0.04666697
p_int: 0.995248215
p_ni: 0.004751785
Score: 0.619
Data Source: BioPlex,STRINGDB
SRP54
Tbio
Novelty: 0.00535567
p_int: 0.993692152
p_ni: 0.006307848
Score: 0.806
Data Source: BioPlex,STRINGDB
CTNNA3
Tbio
Novelty: 0.01472452
p_int: 0.991946748
p_ni: 0.000173575
p_wrong: 0.007879676
Score: 0.163
Data Source: BioPlex,STRINGDB
POLR3E
Tbio
Family: Enzyme
Novelty: 0.06500715
p_int: 0.959155755
p_ni: 0.040844245
Score: 0.167
Data Source: BioPlex,STRINGDB
GIMAP4
Tbio
Family: Enzyme
Novelty: 0.06861132
Score: 0.92
Data Source: STRINGDB
GIMAP5
Tbio
Family: Enzyme
Novelty: 0.02264797
Score: 0.838
Data Source: STRINGDB
GIMAP6
Tbio
Family: Enzyme
Novelty: 0.18744467
Score: 0.829
Data Source: STRINGDB
GIMAP7
Tbio
Family: Enzyme
Novelty: 0.15758026
Score: 0.788
Data Source: STRINGDB
CARNS1
Tbio
Family: Enzyme
Novelty: 0.09322055
Score: 0.745
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.53

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer