You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
NAXE
NAD(P)H-hydrate epimerase

Protein Summary
Description
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368235
  • ENSP00000357218
  • ENSG00000163382

Symbol
  • AIBP
  • APOA1BP
  • YJEFN1
  • AIBP
  • PEBEL
  • YJEFN1
  • APOA1BP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.56   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 201   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.56   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 201   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
NAD(P)HX epimerase
VGNC:92
457399
Macaque
NAD(P)HX epimerase
718532
Mouse
MGI:2180167
246703
Rat
RGD:1304699
295229
Dog
NAD(P)HX epimerase
VGNC:53623
612116
Species
Name
OMA
EggNOG
Inparanoid
Chimp
NAD(P)HX epimerase
Macaque
NAD(P)HX epimerase
Mouse
Rat
Dog
NAD(P)HX epimerase
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NCW5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (6)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Metabolism of vitamins and cofactors
Reactome
Metabolism of water-soluble vitamins and cofactors
Reactome
Nicotinamide salvaging
Reactome
Nicotinate metabolism
Name
Explore in Pharos
Explore in Source
Metabolism
Metabolism of vitamins and cofactors
Metabolism of water-soluble vitamins and cofactors
Nicotinamide salvaging
Nicotinate metabolism
Gene Ontology Terms (18)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (62)
1 – 10 of 62
NAXD
Tbio
Family: Enzyme
Novelty: 0.07681941
Score: 0.994
Data Source: STRINGDB
GAPDH
Tchem
Family: Enzyme
Novelty: 0.00005849
Score: 0.902
Data Source: STRINGDB
PYGB
Tbio
Family: Enzyme
Novelty: 0.00224148
Score: 0.895
Data Source: STRINGDB
DDX6
Tbio
Family: Enzyme
Novelty: 0.01032357
Score: 0.835
Data Source: STRINGDB
FADD
Tbio
Novelty: 0.00137968
Score: 0.833
Data Source: STRINGDB
APOA1
Tbio
Novelty: 0.0001216
Score: 0.833
Data Source: STRINGDB
DCP2
Tbio
Family: Enzyme
Novelty: 0.00661786
Score: 0.831
Data Source: STRINGDB
LRP2
Tbio
Novelty: 0.00143258
Score: 0.746
Data Source: STRINGDB
GBE1
Tbio
Family: Enzyme
Novelty: 0.00233237
Score: 0.688
Data Source: STRINGDB
DCP1A
Tbio
Novelty: 0.02038933
Score: 0.653
Data Source: STRINGDB
Publication Statistics
PubMed Score  19.56

PubMed score by year
PubTator Score  11.45

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer