You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
C11orf65
Uncharacterized protein C11orf65

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393084
  • ENSP00000376799
  • ENSG00000166323
  • ENST00000525729
  • ENSP00000433395
  • ENST00000527531
  • ENSP00000431706
  • ENST00000529391
  • ENSP00000436400
  • ENST00000615746
  • ENSP00000483537
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (12)
1 – 10 of 12
UBE2T
Tbio
Novelty:  0.02718799
p_int:  0.931836625
p_ni:  0.067252343
p_wrong:  0.000911032
Score:  0.282
Data Source:  BioPlex,STRINGDB
LASP1
Tbio
Novelty:  0.00960538
p_int:  0.852276473
p_ni:  0.147723525
p_wrong:  2e-9
Score:  0.319
Data Source:  BioPlex,STRINGDB
KDELC2
Tdark
Novelty:  0.7820617
Score:  0.814
Data Source:  STRINGDB
EXPH5
Tbio
Novelty:  0.07504682
Score:  0.685
Data Source:  STRINGDB
SUMO1
Tbio
Novelty:  0.00137629
Score:  0.547
Data Source:  STRINGDB
DCAF4L2
Tdark
Novelty:  0.55635961
Score:  0.529
Data Source:  STRINGDB
NPAT
Tbio
Novelty:  0.01063979
Score:  0.477
Data Source:  STRINGDB
CUL5
Tbio
Novelty:  0.00792494
Score:  0.455
Data Source:  STRINGDB
IKZF5
Tbio
Family:  TF
Novelty:  0.36596327
Score:  0.44
Data Source:  STRINGDB
TNFAIP8L3
Tbio
Novelty:  0.1079383
Score:  0.433
Data Source:  STRINGDB
GWAS Traits (33)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
3
3
3
93.4
mean corpuscular hemoglobin concentration
2
2
2
92.5
platelet crit
1
2
2
90.8
red blood cell density measurement
2
2
2
90.8
mean reticulocyte volume
1
2
2
85.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
3
93.4
mean corpuscular hemoglobin concentration
2
92.5
platelet crit
2
90.8
red blood cell density measurement
2
90.8
mean reticulocyte volume
2
85.8
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf65 homolog
VGNC:3183
736747
Macaque
chromosome 14 open reading frame, human C11orf65
707988
Mouse
MGI:1922561
75311
Rat
RGD:1311251
315665
Dog
chromosome 5 C11orf65 homolog
VGNC:53307
611544
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 11 C11orf65 homolog
Macaque
chromosome 14 open reading frame, human C11orf65
Mouse
Rat
Dog
chromosome 5 C11orf65 homolog
Publication Statistics
PubMed Score 1.14
PubMed score by year
PubTator Score 0.50
PubTator score by year