Tdark SPRYD3 SPRY domain-containing protein 3

Protein Summary

Uniprot Accession IDs

• Q8NCJ5
• B9EG99
• Q96SK5

Gene Name

• SPRYD3

Ensembl ID

• ENST00000301463
• ENSP00000301463
• ENSG00000167778

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
cell type or tissue	0.77
disease perturbation	0.62
transcription factor binding site profile	0.52
tissue	0.49

Protein Classes

PANTHER Classes

Protein / Transporter / Spry Domain-containing Protein 3

Protein / Transfer/carrier Protein / Spry Domain-containing Protein 3

DTO Classes

Protein / Transporter / Spry Domain-containing Protein 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.38   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 53   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.38   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0