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Tbio
RELL2
RELT-like protein 2

Protein Summary
Description
Induces activation of MAPK14/p38 cascade, when overexpressed (PubMed:28688764). Induces apoptosis, when overexpressed (PubMed:19969290).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297164
  • ENSP00000297164
  • ENSG00000164620
  • ENST00000444782
  • ENSP00000409443

Symbol
  • C5orf16
  • C5orf16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
tissue sample
0.55
transcription factor binding site profile
0.55
cell line
0.5
transcription factor
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.16   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.16   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (25)
1 – 10 of 25
TRIM9
Tbio
Family: Enzyme
Novelty: 0.06250762
p_int: 0.999999964
p_ni: 3.6e-8
Score: 0.186
Data Source: BioPlex,STRINGDB
OXSR1
Tbio
Family: Kinase
Novelty: 0.11142923
p_int: 0.999999327
p_ni: 6.73e-7
Score: 0.912
Data Source: BioPlex,STRINGDB
LRR1
Tbio
Novelty: 0.02407468
p_int: 0.99999633
p_ni: 0.000003636
p_wrong: 3.4e-8
Data Source: BioPlex
STK39
Tbio
Family: Kinase
Novelty: 0.00548476
p_int: 0.99999624
p_ni: 0.00000376
Score: 0.753
Data Source: BioPlex,STRINGDB
RELT
Tbio
Novelty: 0.07977949
p_int: 0.999858482
p_ni: 0.000141471
p_wrong: 4.7e-8
Score: 0.759
Data Source: BioPlex,STRINGDB
AGBL5
Tbio
Family: Enzyme
Novelty: 0.05735805
p_int: 0.999852607
p_ni: 0.000146216
p_wrong: 0.000001177
Score: 0.189
Data Source: BioPlex,STRINGDB
MCM10
Tbio
Novelty: 0.0136058
p_int: 0.999643526
p_ni: 0.000356473
p_wrong: 1e-9
Data Source: BioPlex
MGST2
Tbio
Family: Enzyme
Novelty: 0.04976733
p_int: 0.999522281
p_ni: 0.000107057
p_wrong: 0.000370662
Score: 0.269
Data Source: BioPlex,STRINGDB
HSPA14
Tbio
Novelty: 0.01714625
p_int: 0.999152566
p_ni: 0.000847434
Score: 0.152
Data Source: BioPlex,STRINGDB
DNAH14
Tdark
Novelty: 0.28289652
p_int: 0.998849234
p_ni: 0.001142615
p_wrong: 0.000008151
Score: 0.179
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  2.16

PubMed score by year
PubTator Score  0.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer