ACBD4
Acyl-CoA-binding domain-containing protein 4
Protein Summary
Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters. This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- ENST00000321854
- ENSP00000314440
- ENSG00000181513
- ENST00000376955
- ENSP00000366154
- ENST00000398322
- ENSP00000381367
- ENST00000431281
- ENSP00000405969
- ENST00000586346
- ENSP00000465484
- ENST00000591859
- ENSP00000465610
- ENST00000619916
- ENSP00000482750
- HMFT0700
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.84 | ||
transcription factor | 0.78 | ||
histone modification site profile | 0.66 | ||
cellular component | 0.64 | ||
cell type or tissue | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.45 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 129 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.45 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 129 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0