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Tbio
SCCPDH
Saccharopine dehydrogenase-like oxidoreductase

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366510
  • ENSP00000355467
  • ENSG00000143653

Symbol
  • NET11
  • CGI-49
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.84
gene perturbation
0.81
tissue sample
0.77
disease perturbation
0.74
PubMedID
0.71


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.89   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.89   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
1
1
1
16.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
1
16.4
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
saccharopine dehydrogenase (putative)
VGNC:9898
469737
Macaque
saccharopine dehydrogenase (putative)
702924
Mouse
MGI:1924486
109232
Rat
RGD:1311440
305021
Dog
saccharopine dehydrogenase (putative) [Source:HGNC Symbol;Acc:HGNC:24275]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
saccharopine dehydrogenase (putative)
Macaque
saccharopine dehydrogenase (putative)
Mouse
Rat
Dog
saccharopine dehydrogenase (putative) [Source:HGNC Symbol;Acc:HGNC:24275]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NBX0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Gene Ontology Terms (11)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (134)
1 – 10 of 134
USP13
Tchem
Family: Enzyme
Novelty: 0.03470844
p_int: 0.999999628
p_ni: 4e-8
p_wrong: 3.32e-7
Score: 0.2
Data Source: BioPlex,STRINGDB
PEX19
Tbio
Novelty: 0.00605342
p_int: 0.999979075
p_ni: 0.000020925
Data Source: BioPlex
DNAJB11
Tbio
Novelty: 0.02588745
p_int: 0.999883354
p_ni: 0.000116646
Data Source: BioPlex
PDE4DIP
Tbio
Novelty: 0.03414104
p_int: 0.998753093
p_ni: 0.001246819
p_wrong: 8.8e-8
Data Source: BioPlex
RAB4A
Tbio
Family: Enzyme
Novelty: 0.00423197
p_int: 0.997943488
p_ni: 0.002056505
p_wrong: 7e-9
Score: 0.2
Data Source: BioPlex,STRINGDB
APOA2
Tbio
Novelty: 0.00117627
p_int: 0.996555591
p_ni: 0.003444409
Data Source: BioPlex
IFT20
Tbio
Novelty: 0.03005088
p_int: 0.996127595
p_ni: 0.003872011
p_wrong: 3.94e-7
Data Source: BioPlex
PPP6R2
Tbio
Family: Enzyme
Novelty: 0.12886225
p_int: 0.99583431
p_ni: 0.004164796
p_wrong: 8.95e-7
Score: 0.166
Data Source: BioPlex,STRINGDB
WAPL
Tbio
Novelty: 0.01598061
p_int: 0.99153089
p_ni: 0.00846911
Data Source: BioPlex
BZW2
Tbio
Novelty: 0.17006204
p_int: 0.987601171
p_ni: 0.012396554
p_wrong: 0.000002274
Data Source: BioPlex
Publication Statistics
PubMed Score  10.89

PubMed score by year
PubTator Score  0.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer