Tbio AQP11 Aquaporin-11

Protein Summary

Description

Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.

Uniprot Accession IDs

• Q8NBQ7
• AQP-11

Gene Name

• AQP11

Ensembl ID

• ENST00000313578
• ENSP00000318770
• ENSG00000178301

Symbol

• AQPX1
• AQPX1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
cellular component	0.71
cell type or tissue	0.67
transcription factor binding site profile	0.67
protein domain	0.58

Protein Classes

DTO Classes

Protein / Ion Channel / Other Ion Channel / Aquaporin / Aquaporin-11

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.25   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 95   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.25   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0