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Tdark
TTC13
Tetratricopeptide repeat protein 13

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366661
  • ENSP00000355621
  • ENSG00000143643
  • ENST00000366662
  • ENSP00000355622
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
transcription factor binding site profile
0.81
transcription factor perturbation
0.8
cell line
0.66
kinase perturbation
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
60.2
mean platelet volume
1
1
1
51.4
hemoglobin measurement
1
1
1
44.2
venous thromboembolism
2
1
1
1.3
17.8
soluble triggering receptor expressed on myeloid cells 2 measurement
1
1
0
8832.8
0.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
60.2
mean platelet volume
1
51.4
hemoglobin measurement
1
44.2
venous thromboembolism
1
1.3
17.8
soluble triggering receptor expressed on myeloid cells 2 measurement
0
8832.8
0.7
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 13
VGNC:10915
469149
Macaque
tetratricopeptide repeat domain 13
714027
Mouse
MGI:2384573
234875
Rat
RGD:1310186
292095
Dog
tetratricopeptide repeat domain 13
VGNC:47938
488976
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 13
Macaque
tetratricopeptide repeat domain 13
Mouse
Rat
Dog
tetratricopeptide repeat domain 13
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NBP0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (28)
1 – 10 of 28
OR4K15
Tdark
Family:  oGPCR
Novelty:  2.54386907
Score:  0.815
Data Source:  STRINGDB
TPGS1
Tdark
Family:  Enzyme
Novelty:  0.38252921
Score:  0.775
Data Source:  STRINGDB
RNF217
Tdark
Family:  Enzyme
Novelty:  0.37676903
Score:  0.768
Data Source:  STRINGDB
TTC8
Tbio
Novelty:  0.08520636
Score:  0.75
Data Source:  STRINGDB
NAA20
Tbio
Family:  Enzyme
Novelty:  0.07814789
Score:  0.714
Data Source:  STRINGDB
UBR7
Tbio
Family:  Epigenetic
Novelty:  0.23270052
Score:  0.69
Data Source:  STRINGDB
RNF19B
Tbio
Family:  Enzyme
Novelty:  0.20054824
Score:  0.667
Data Source:  STRINGDB
TRIM67
Tdark
Novelty:  0.02511888
Score:  0.663
Data Source:  STRINGDB
SORCS1
Tbio
Novelty:  0.03148473
Score:  0.663
Data Source:  STRINGDB
PITRM1
Tchem
Family:  Enzyme
Novelty:  0.08067518
Score:  0.645
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.47

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer