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Tdark
FAM184A
Protein FAM184A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338891
  • ENSP00000342604
  • ENSG00000111879
  • ENST00000352896
  • ENSP00000326608
  • ENST00000521531
  • ENSP00000430442

Symbol
  • C6orf60
  • C6orf60
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
tissue sample
0.64
small molecule perturbation
0.6
tissue
0.55
transcription factor binding site profile
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
1
1
87.5
1
1
1
33.4
self reported educational attainment
1
1
1
33.4
intelligence
1
1
1
33.4
electrocardiography
1
1
3
15.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
87.5
1
33.4
self reported educational attainment
1
33.4
intelligence
1
33.4
electrocardiography
3
15.1
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (14)
1 – 10 of 14
CDR2
Tbio
Novelty: 0.00141419
p_int: 0.999999988
p_ni: 3e-9
p_wrong: 9e-9
Score: 0.224
Data Source: BioPlex,STRINGDB
LRRC61
Tdark
Novelty: 1.45343096
p_int: 0.99999982
p_ni: 1.8e-7
Data Source: BioPlex
PLEKHO2
Tdark
Novelty: 0.48296621
p_int: 0.999996073
p_ni: 0.000003911
p_wrong: 1.6e-8
Score: 0.332
Data Source: BioPlex,STRINGDB
PROM2
Tbio
Novelty: 0.0446718
Score: 0.62
Data Source: STRINGDB
CEP95
Tdark
Novelty: 1.18897795
Score: 0.566
Data Source: STRINGDB
CAMTA2
Tbio
Family: TF
Novelty: 0.06741618
Score: 0.557
Data Source: STRINGDB
ANAPC7
Tbio
Family: Enzyme
Novelty: 0.17956785
Score: 0.526
Data Source: STRINGDB
CEP250
Tbio
Novelty: 0.08014712
Score: 0.512
Data Source: STRINGDB
LRRC8D
Tbio
Novelty: 0.10536285
Score: 0.497
Data Source: STRINGDB
C9orf131
Tdark
Novelty: 17.32394366
Score: 0.494
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.33

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer