Tbio PRPF38A Pre-mRNA-splicing factor 38A

Protein Summary

Description

Involved in pre-mRNA splicing as a component of the spliceosome.

Uniprot Accession IDs

• Q8NAV1
• Q96JW1
• Q9BVZ8

Gene Name

• PRPF38A

Ensembl ID

• ENST00000257181
• ENSP00000257181
• ENSG00000134748

Symbol

• Prp38
• PRP38A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.97
histone modification site profile	0.93
transcription factor perturbation	0.91
drug perturbation	0.71
transcription factor binding site profile	0.7

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.36   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 101   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.36   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0