Tbio FSIP1 Fibrous sheath-interacting protein 1

Protein Summary

Uniprot Accession IDs

• Q8NA03
• Q6X2C8
• Q86Y89

Gene Name

• FSIP1

Ensembl ID

• ENST00000350221
• ENSP00000280236
• ENSG00000150667

Symbol

• HSD10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.66
disease perturbation	0.62
trait	0.61
transcription factor binding site profile	0.55
cell line	0.5

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.64   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 172   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.64   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Protein-Protein Interactions (61)

Explore Interacting Targets

1 – 10 of 61

• See Interactions on String-DB

HSD17B10

Tchem

Family: Enzyme

Novelty: 0.00657996

Score: 0.834

Data Source: STRINGDB

AKAP4

Tbio

Family: Enzyme

Novelty: 0.00995913

Score: 0.818

Data Source: STRINGDB

FSIP2

Tdark

Novelty: 0.4434546

Score: 0.81

Data Source: STRINGDB

DHRS11

Tbio

Family: Enzyme

Novelty: 0.00406675

Score: 0.757

Data Source: STRINGDB

TRMT10C

Tbio

Family: Enzyme

Novelty: 0.15151515

Score: 0.71

Data Source: STRINGDB

KIAA0391

Tbio

Family: Enzyme

Novelty: 0.01337196

Score: 0.669

Data Source: STRINGDB

AKAP3

Tbio

Family: Enzyme

Novelty: 0.03957243

Score: 0.66

Data Source: STRINGDB

RIBC1

Tdark

Novelty: 0.55837563

Score: 0.655

Data Source: STRINGDB

HADH

Tbio

Family: Enzyme

Novelty: 0.00360431

Score: 0.63

Data Source: STRINGDB

ROPN1

Tbio

Novelty: 0.07247224

Score: 0.607

Data Source: STRINGDB

Publication Statistics

PubMed Score  37.64

PubMed score by year

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PubTator Score  22.9

PubTator score by year

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Amino Acid Sequence

Residue Counts

Protein Sequence

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