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Tdark
ZNF557
Zinc finger protein 557

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252840
  • ENSP00000252840
  • ENSG00000130544
  • ENST00000414706
  • ENSP00000404065
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.7
cell type or tissue
0.59
protein domain
0.58
microRNA
0.55
cellular component
0.52


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.23   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.23   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 557
VGNC:2144
455648
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 557
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (18)
1 – 10 of 18
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
MBD3L3
Tdark
Novelty: 14.55737705
Score: 0.675
Data Source: STRINGDB
MBD3L4
Tdark
Novelty: 18.46153846
Score: 0.674
Data Source: STRINGDB
OR4F17
Tdark
Family: oGPCR
Novelty: 3.42857143
Score: 0.669
Data Source: STRINGDB
MBD3L5
Tdark
Novelty: 5.85072302
Score: 0.665
Data Source: STRINGDB
SS18L2
Tdark
Novelty: 1.37000973
Score: 0.637
Data Source: STRINGDB
SEC22C
Tdark
Novelty: 0.53697928
Score: 0.584
Data Source: STRINGDB
MIER2
Tbio
Novelty: 0.85226416
Score: 0.56
Data Source: STRINGDB
ZMYM5
Tdark
Novelty: 0.15229851
Score: 0.519
Data Source: STRINGDB
TMEM89
Tdark
Novelty: 43
Score: 0.518
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.23

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer