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Tdark
ANKFN1
Ankyrin repeat and fibronectin type-III domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318698
  • ENSP00000321627
  • ENSG00000153930
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.64
phenotype
0.62
cellular component
0.58
protein domain
0.58
cell line
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.71   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 17   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.71   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 17   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
SRSF12
Tbio
Novelty:  0.34992606
Score:  0.705
Data Source:  STRINGDB
OR8K3
Tdark
Family:  oGPCR
Novelty:  3.18150303
Score:  0.693
Data Source:  STRINGDB
RIMS3
Tbio
Novelty:  0.06922952
Score:  0.665
Data Source:  STRINGDB
C2CD2
Tdark
Novelty:  0.34079266
Score:  0.643
Data Source:  STRINGDB
KRT32
Tdark
Novelty:  1.12077627
Score:  0.587
Data Source:  STRINGDB
GABRR2
Tchem
Family:  IC
Novelty:  0.01651914
Score:  0.577
Data Source:  STRINGDB
TMEM200A
Tdark
Novelty:  0.25580793
Score:  0.577
Data Source:  STRINGDB
SLC35G1
Tbio
Family:  Transporter
Novelty:  0.06448845
Score:  0.572
Data Source:  STRINGDB
MRNIP
Tbio
Novelty:  0.34795518
Score:  0.556
Data Source:  STRINGDB
ARHGAP35
Tbio
Family:  Enzyme
Novelty:  0.00970784
Score:  0.554
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
5
8
97.8
vital capacity
1
1
1
70.5
forced expiratory volume
1
1
1
69.8
chronotype measurement
1
1
1
52
body height
1
2
2
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
8
97.8
vital capacity
1
70.5
forced expiratory volume
1
69.8
chronotype measurement
1
52
body height
2
48.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat and fibronectin type III domain containing 1
VGNC:6335
455144
Macaque
ankyrin repeat and fibronectin type III domain containing 1
707235
Mouse
MGI:2686021
382543
Dog
ankyrin repeat and fibronectin type III domain containing 1
VGNC:37871
491099
Horse
ankyrin repeat and fibronectin type III domain containing 1
VGNC:15311
100070645
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat and fibronectin type III domain containing 1
Macaque
ankyrin repeat and fibronectin type III domain containing 1
Mouse
Dog
ankyrin repeat and fibronectin type III domain containing 1
Horse
ankyrin repeat and fibronectin type III domain containing 1
Publication Statistics
PubMed Score 2.71
PubMed score by year
PubTator Score 1.25
PubTator score by year
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Related Publications
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PMID
Year
Title