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Tdark
ZNF713
Zinc finger protein 713

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene contains C2H2 zinc finger domains. In some individuals, a CGG-repeat expansion from 5-22 repeats to 68-450 repeats has been identified in the first intron of this gene. This mutation is thought to effect the expression of this gene and it has been proposed that it may be associated with Autistic Spectrum Disorder. [provided by RefSeq, Jul 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000633730
  • ENSP00000487818
  • ENSG00000178665
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.63
tissue
0.61
protein domain
0.58
cell type or tissue
0.53
cell line
0.44


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.903
Data Source:  STRINGDB
NIPSNAP2
Tbio
Novelty:  0.0908929
Score:  0.733
Data Source:  STRINGDB
CHCHD2
Tbio
Novelty:  0.01615338
Score:  0.719
Data Source:  STRINGDB
PHKG1
Tchem
Family:  Kinase
Novelty:  0.08576384
Score:  0.66
Data Source:  STRINGDB
CCT6A
Tbio
Novelty:  0.02368046
Score:  0.651
Data Source:  STRINGDB
VSTM2A
Tbio
Novelty:  0.34891628
Score:  0.645
Data Source:  STRINGDB
SEPT14
Tbio
Novelty:  0.07155096
Score:  0.634
Data Source:  STRINGDB
PSPH
Tbio
Family:  Enzyme
Novelty:  0.01078634
Score:  0.615
Data Source:  STRINGDB
LANCL2
Tchem
Novelty:  0.06086418
Score:  0.604
Data Source:  STRINGDB
MRPS17
Tdark
Novelty:  0.46103276
Score:  0.587
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
amino acid measurement
3
5
9
91.5
glycine measurement
3
2
3
90.8
lymphocyte count
2
2
2
86.1
blood metabolite measurement
2
1
2
69.8
body height
1
1
1
67.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
amino acid measurement
9
91.5
glycine measurement
3
90.8
lymphocyte count
2
86.1
blood metabolite measurement
2
69.8
body height
1
67.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 713
VGNC:14123
742558
Dog
zinc finger protein 713
VGNC:48807
606818
Horse
zinc finger protein 713
VGNC:25380
100061119
Cow
zinc finger protein 713
VGNC:37338
100126443
Pig
zinc finger protein 713
100521127
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 713
Dog
zinc finger protein 713
Horse
zinc finger protein 713
Cow
zinc finger protein 713
Pig
zinc finger protein 713
Publication Statistics
PubMed Score 1.74
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title