You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF676
Zinc finger protein 676

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395385
  • ENSP00000378783
  • ENSG00000276219
  • ENST00000397121
  • ENSP00000380310
  • ENSG00000196109
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.82
tissue sample
0.78
protein domain
0.58
tissue
0.57
cell line
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.31   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.31   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
telomere length
2
2
2
56.6
telomere length
2
2
2
56.6
1
1
0
1.2
21.5
1
1
0
1.2
21.5
triglyceride measurement
1
1
1
0.5
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
telomere length
2
56.6
telomere length
2
56.6
0
1.2
21.5
0
1.2
21.5
triglyceride measurement
1
0.5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N7Q3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (22)
1 – 10 of 22
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.904
Data Source:  STRINGDB
CTC1
Tbio
Novelty:  0.01298038
Score:  0.715
Data Source:  STRINGDB
STN1
Tbio
Novelty:  0.01309587
Score:  0.672
Data Source:  STRINGDB
ACYP2
Tbio
Family:  Enzyme
Novelty:  0.03063981
Score:  0.583
Data Source:  STRINGDB
DCAF4
Tbio
Novelty:  0.24190895
Score:  0.582
Data Source:  STRINGDB
CFAP57
Tdark
Novelty:  0.33594432
Score:  0.565
Data Source:  STRINGDB
MBLAC1
Tdark
Family:  Enzyme
Novelty:  0.48250122
Score:  0.547
Data Source:  STRINGDB
RTEL1
Tbio
Family:  Enzyme
Novelty:  0.00761538
Score:  0.533
Data Source:  STRINGDB
OR5M11
Tdark
Family:  oGPCR
Novelty:  6.70980007
Score:  0.53
Data Source:  STRINGDB
DHX35
Tdark
Family:  Enzyme
Novelty:  0.26052594
Score:  0.516
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.31

PubMed score by year
PubTator Score  1.57

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer