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Tdark
SERP2
Stress-associated endoplasmic reticulum protein 2

Protein Summary
Description
May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379179
  • ENSP00000368477
  • ENSG00000151778

Symbol
  • C13orf21
  • C13orf21
  • bA269C23.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.65
gene perturbation
0.62
tissue sample
0.62
cellular component
0.47
transcription factor
0.47


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 1   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 1   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1919911
72661
Dog
stress associated endoplasmic reticulum protein family member 2
VGNC:46023
100856132
Opossum
stress associated endoplasmic reticulum protein family member 2 [Source:HGNC Symbol;Acc:HGNC:20607]
Xenopus
stress-associated endoplasmic reticulum protein family member 2
XB-GENE-954859
779835
Zebrafish
ZDB-GENE-081104-143
100319240
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
stress associated endoplasmic reticulum protein family member 2
Opossum
stress associated endoplasmic reticulum protein family member 2 [Source:HGNC Symbol;Acc:HGNC:20607]
Xenopus
stress-associated endoplasmic reticulum protein family member 2
Zebrafish
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (25)
1 – 10 of 25
SEC61B
Tbio
Novelty: 0.08622222
Score: 0.822
Data Source: STRINGDB
SEC11C
Tdark
Family: Enzyme
Novelty: 0.19577003
Score: 0.822
Data Source: STRINGDB
LRRC9
Tdark
Novelty: 0.59020229
Score: 0.802
Data Source: STRINGDB
SPCS1
Tbio
Family: Enzyme
Novelty: 0.0731223
Score: 0.775
Data Source: STRINGDB
TMED10
Tbio
Novelty: 0.02742083
Score: 0.699
Data Source: STRINGDB
TMED6
Tdark
Novelty: 0.598611
Score: 0.676
Data Source: STRINGDB
DAD1
Tbio
Family: Enzyme
Novelty: 0.00653242
Score: 0.662
Data Source: STRINGDB
SPCS2
Tdark
Family: Enzyme
Novelty: 0.21358992
Score: 0.638
Data Source: STRINGDB
TXLNB
Tbio
Novelty: 0.12751933
Score: 0.62
Data Source: STRINGDB
RPS15
Tbio
Novelty: 0.00635155
Score: 0.605
Data Source: STRINGDB
Publication Statistics
PubMed Score  12.20

PubMed score by year
PubTator Score  6.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer