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Tbio
METTL13
Methyltransferase-like protein 13

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361735
  • ENSP00000354920
  • ENSG00000010165
  • ENST00000362019
  • ENSP00000355393
  • ENST00000367737
  • ENSP00000356711

Symbol
  • KIAA0859
  • feat
  • CGI-01
  • DFNB26
  • DFNB26M
  • METTL13
  • KIAA0859
  • 5630401D24Rik
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
kinase perturbation
0.93
transcription factor perturbation
0.84
disease perturbation
0.83
transcription factor binding site profile
0.81


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.68   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.68   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
1
1
0
5.9
31.4
mean platelet volume
1
1
1
29.8
self reported educational attainment
1
1
1
2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
0
5.9
31.4
mean platelet volume
1
29.8
self reported educational attainment
1
2
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 13
VGNC:10717
456446
Macaque
methyltransferase like 13
704943
Mouse
MGI:1918699
71449
Dog
methyltransferase like 13
490342
Horse
methyltransferase like 13
VGNC:20119
100052265
Species
Name
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 13
Macaque
methyltransferase like 13
Mouse
Dog
methyltransferase like 13
Horse
methyltransferase like 13
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q8N6R0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (72)
1 – 10 of 72
KLK5
Tchem
Family:  Enzyme
Novelty:  0.00835407
p_int:  0.951673502
p_ni:  0.048326498
Score:  0.183
Data Source:  BioPlex,STRINGDB
FAS
Tbio
Novelty:  0.00043286
p_int:  0.950594174
p_ni:  0.049405826
Score:  0.183
Data Source:  BioPlex,STRINGDB
HLA-E
Tbio
Novelty:  0.00216583
p_int:  0.931065886
p_ni:  0.068934114
Score:  0.185
Data Source:  BioPlex,STRINGDB
SERPINB4
Tbio
Novelty:  0.00522283
p_int:  0.887812322
p_ni:  0.112187673
p_wrong:  5e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
SIGLEC5
Tbio
Novelty:  0.02616618
p_int:  0.833412358
p_ni:  0.166587642
Score:  0.228
Data Source:  BioPlex,STRINGDB
TMCO3
Tdark
Novelty:  1.16719823
p_int:  0.753504026
p_ni:  0.246495973
p_wrong:  2e-9
Data Source:  BioPlex
ANKMY2
Tdark
Novelty:  0.50777631
Score:  0.869
Data Source:  STRINGDB
EEF1AKMT2
Tbio
Family:  Enzyme
Novelty:  0.13586312
Score:  0.782
Data Source:  STRINGDB
NDUFAF7
Tbio
Family:  Enzyme
Novelty:  0.24691414
Score:  0.733
Data Source:  STRINGDB
PRRC2C
Tbio
Novelty:  0.25128003
Score:  0.714
Data Source:  STRINGDB
Publication Statistics
PubMed Score  9.68

PubMed score by year
PubTator Score  8.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer