Tbio SLC15A4 Solute carrier family 15 member 4

Protein Summary

Description

Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides.

Uniprot Accession IDs

• Q8N697
• A6H8Y9
• B3KTK1
• Q71M34
• Q7Z5F8
• Q8TAH0

Gene Name

• SLC15A4

Ensembl ID

• ENST00000266771
• ENSP00000266771
• ENSG00000139370

Symbol

• PHT1
• PTR4
• PHT1
• PTR4
• FP12591

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.88
transcription factor perturbation	0.88
virus perturbation	0.85
transcription factor binding site profile	0.79
molecular function	0.76

Protein Classes

PANTHER Classes

Protein / Transporter / Solute Carrier Family 15 Member 4

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc15 Family Of Peptide Transporters / Solute Carrier Family 15 Member 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 98.72   (req: < 5)

Gene RIFs: 19   (req: <= 3)

Antibodies: 63   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 98.72   (req: >= 5)

Gene RIFs: 19   (req: > 3)

Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0