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Tdark
TRAM1L1
Translocating chain-associated membrane protein 1-like 1

Protein Summary
Description
Stimulatory or required for the translocation of secretory proteins across the ER membrane.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310754
  • ENSP00000309402
  • ENSG00000174599
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.74
histone modification site profile
0.74
virus perturbation
0.68
tissue sample
0.64
cellular component
0.57


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
translocation associated membrane protein 1-like 1
704134
Mouse
MGI:2443503
229801
Rat
RGD:1306398
310846
Dog
translocation associated membrane protein 1 like 1
VGNC:49114
487917
Species
Name
OMA
EggNOG
Inparanoid
Macaque
translocation associated membrane protein 1-like 1
Mouse
Rat
Dog
translocation associated membrane protein 1 like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N609-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (17)
1 – 10 of 17
QRFPR
Tchem
Family:  GPCR
Novelty:  0.03650642
Score:  0.702
Data Source:  STRINGDB
CNOT6L
Tbio
Novelty:  0.06038336
Score:  0.674
Data Source:  STRINGDB
KLHL8
Tdark
Novelty:  0.4838314
Score:  0.654
Data Source:  STRINGDB
UGDH
Tbio
Family:  Enzyme
Novelty:  0.00284931
Score:  0.642
Data Source:  STRINGDB
SSR2
Tbio
Novelty:  0.01383689
Score:  0.621
Data Source:  STRINGDB
SSR3
Tbio
Novelty:  0.05838475
Score:  0.62
Data Source:  STRINGDB
NKAIN3
Tdark
Family:  Enzyme
Novelty:  0.3456674
Score:  0.592
Data Source:  STRINGDB
FAM174A
Tdark
Novelty:  0.30693139
Score:  0.56
Data Source:  STRINGDB
NDST4
Tbio
Family:  Enzyme
Novelty:  0.09591294
Score:  0.511
Data Source:  STRINGDB
LUZP2
Tdark
Novelty:  0.34485558
Score:  0.484
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.53

PubMed score by year
PubTator Score  0.64

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer