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Tbio
RFLNB
Refilin-B

Protein Summary
Description
Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in the formation of cartilaginous skeletal elements.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329099
  • ENSP00000331915
  • ENSG00000183688

Symbol
  • CFM1
  • FAM101B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.15   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.15   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
refilin B
VGNC:14194
454401
Mouse
MGI:1923816
76566
Rat
RGD:1359691
287534
Dog
refilin B
VGNC:45498
611214
Horse
refilin B [Source:HGNC Symbol;Acc:HGNC:28705]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
refilin B
Mouse
Rat
Dog
refilin B
Horse
refilin B [Source:HGNC Symbol;Acc:HGNC:28705]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N5W9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Protein-Protein Interactions (26)
1 – 10 of 26
NUDT5
Tbio
Family: Enzyme
Novelty: 0.02550535
p_int: 0.999999995
p_wrong: 5e-9
Data Source: BioPlex
FBLIM1
Tbio
Novelty: 0.0332985
p_int: 0.999997221
p_ni: 0.000002779
Data Source: BioPlex
LAD1
Tbio
Novelty: 0.03059679
p_int: 0.998843408
p_ni: 0.001154428
p_wrong: 0.000002164
Data Source: BioPlex
NPPB
Tbio
Novelty: 0.00024947
p_int: 0.996961602
p_ni: 0.000202663
p_wrong: 0.002835735
Data Source: BioPlex
CAPN6
Tbio
Novelty: 0.04489237
p_int: 0.882580733
p_ni: 0.000003339
p_wrong: 0.117415928
Score: 0.38
Data Source: BioPlex,STRINGDB
FLNA
Tbio
Novelty: 0.00156479
Score: 0.711
Data Source: STRINGDB
KRBOX1
Tdark
Novelty: 3.9375
Score: 0.624
Data Source: STRINGDB
NUSAP1
Tbio
Novelty: 0.01702118
Score: 0.561
Data Source: STRINGDB
CFTR
Tclin
Family: IC
Novelty: 0.00012639
Score: 0.542
Data Source: STRINGDB
GRXCR1
Tdark
Novelty: 0.17455124
Score: 0.541
Data Source: STRINGDB
Publication Statistics
PubMed Score  10.15

PubMed score by year
PubTator Score  0.91

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer