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Tdark
FAM24B
Protein FAM24B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368896
  • ENSP00000357892
  • ENSG00000213185
  • ENST00000368898
  • ENSP00000357894
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.72
tissue sample
0.53
tissue
0.47
transcription factor
0.44
disease
0.41


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.88   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.88   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
4
96.5
low density lipoprotein cholesterol measurement
7
5
7
94.7
apolipoprotein B measurement
1
1
1
56.8
mean reticulocyte volume
1
1
1
56
reticulocyte measurement
1
1
1
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
96.5
low density lipoprotein cholesterol measurement
7
94.7
apolipoprotein B measurement
1
56.8
mean reticulocyte volume
1
56
reticulocyte measurement
1
48.5
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 24 member B
VGNC:12327
100610674
Mouse
MGI:1915473
68223
Rat
RGD:1560948
499278
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 24 member B
Mouse
Rat
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N5W8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (76)
1 – 10 of 76
ANXA3
Tbio
Novelty:  0.00615077
p_int:  0.999999887
p_ni:  1.13e-7
Data Source:  BioPlex
ITGB4
Tbio
Novelty:  0.00386461
p_int:  0.999999529
p_ni:  2.92e-7
p_wrong:  1.79e-7
Data Source:  BioPlex
MYOF
Tchem
Novelty:  0.00656314
p_int:  0.999999332
p_ni:  6.2e-8
p_wrong:  6.06e-7
Data Source:  BioPlex
ALDH1A3
Tchem
Family:  Enzyme
Novelty:  0.00691116
p_int:  0.999998914
p_ni:  0.000001086
Data Source:  BioPlex
BLVRB
Tbio
Family:  Enzyme
Novelty:  0.00705559
p_int:  0.999559878
p_ni:  0.000438239
p_wrong:  0.000001884
Data Source:  BioPlex
LASP1
Tbio
Novelty:  0.00960538
p_int:  0.999548052
p_ni:  0.000451947
p_wrong:  1e-9
Data Source:  BioPlex
POTEF
Tbio
Novelty:  0.00191599
p_int:  0.999210546
p_ni:  0.000789454
Data Source:  BioPlex
DDX46
Tbio
Family:  Enzyme
Novelty:  0.02888527
p_int:  0.998778559
p_ni:  0.001221441
Data Source:  BioPlex
CRABP2
Tchem
Novelty:  0.0050363
p_int:  0.998395501
p_ni:  0.00031543
p_wrong:  0.001289069
Data Source:  BioPlex
RBP1
Tbio
Novelty:  0.00199929
p_int:  0.998345371
p_ni:  0.00088677
p_wrong:  0.000767859
Data Source:  BioPlex
Publication Statistics
PubMed Score  0.88

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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