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Tdark
C2orf73
Uncharacterized protein C2orf73

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 9   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 9   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
ABRAXAS2
Tbio
Novelty:  0.20430604
p_int:  0.99983852
p_ni:  0.000161479
Data Source:  BioPlex
MGME1
Tbio
Family:  Enzyme
Novelty:  0.05284418
p_int:  0.990921901
p_ni:  0.009078099
Data Source:  BioPlex
ATG3
Tbio
Novelty:  0.00541077
p_int:  0.990233015
p_ni:  0.005668426
p_wrong:  0.00409856
Data Source:  BioPlex
BABAM2
Tbio
Novelty:  0.00448485
p_int:  0.983074203
p_ni:  0.016925797
Data Source:  BioPlex
BABAM1
Tbio
Novelty:  0.03812501
p_int:  0.958684349
p_ni:  0.041315644
p_wrong:  7e-9
Data Source:  BioPlex
MTHFD2
Tchem
Family:  Enzyme
Novelty:  0.01776594
p_int:  0.866612985
p_ni:  0.133387015
Data Source:  BioPlex
C17orf98
Tdark
Novelty:  1.86890404
Score:  0.638
Data Source:  STRINGDB
C6orf201
Tdark
Novelty:  51
Score:  0.63
Data Source:  STRINGDB
TSPYL6
Tdark
Novelty:  0.68478376
Score:  0.596
Data Source:  STRINGDB
FAM71E1
Tdark
Novelty:  1.60714286
Score:  0.589
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
5
9
98.8
alkaline phosphatase measurement
2
2
1
8.9
79.7
bone density
3
2
3
71.2
glomerular filtration rate
2
2
1
6.2
60.8
bone quantitative ultrasound measurement
3
1
4
58.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
9
98.8
alkaline phosphatase measurement
1
8.9
79.7
bone density
3
71.2
glomerular filtration rate
1
6.2
60.8
bone quantitative ultrasound measurement
4
58.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 2A C2orf73 homolog
VGNC:10439
741198
Macaque
chromosome 13 open reading frame, human C2orf73
718692
Mouse
MGI:1922337
75087
Rat
RGD:1562229
498431
Dog
chromosome 10 C2orf73 homolog
VGNC:54279
474596
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 2A C2orf73 homolog
Macaque
chromosome 13 open reading frame, human C2orf73
Mouse
Rat
Dog
chromosome 10 C2orf73 homolog
Publication Statistics
PubMed Score 0.85
PubMed score by year
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Related Publications
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PMID
Year
Title