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Tdark
RAB42
Ras-related protein Rab-42

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373826
  • ENSP00000362932
  • ENSG00000188060
  • ENST00000465518
  • ENSP00000491546
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
transcription factor
0.57
cell type or tissue
0.51
tissue sample
0.47
histone modification site profile
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.73   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.73   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (83)
RAB27B
Tbio
Family:  Enzyme
Novelty:  0.01530218
Score:  0.949
Data Source:  STRINGDB
RAB38
Tbio
Family:  Enzyme
Novelty:  0.02651645
Score:  0.945
Data Source:  STRINGDB
RAB44
Tdark
Family:  Enzyme
Novelty:  0.16987153
Score:  0.945
Data Source:  STRINGDB
RAB27A
Tchem
Family:  Enzyme
Novelty:  0.00369416
Score:  0.941
Data Source:  STRINGDB
CHM
Tbio
Family:  Enzyme
Novelty:  0.00226278
Score:  0.94
Data Source:  STRINGDB
CHML
Tbio
Family:  Enzyme
Novelty:  0.00509709
Score:  0.939
Data Source:  STRINGDB
RAB21
Tbio
Family:  Enzyme
Novelty:  0.03221825
Score:  0.938
Data Source:  STRINGDB
RAB20
Tbio
Family:  Enzyme
Novelty:  0.06768944
Score:  0.937
Data Source:  STRINGDB
RAB6A
Tchem
Family:  Enzyme
Novelty:  0.00546034
Score:  0.935
Data Source:  STRINGDB
RAB18
Tbio
Family:  Enzyme
Novelty:  0.01548795
Score:  0.932
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
RAB geranylgeranylation
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational protein modification
RAB geranylgeranylation
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil count
2
2
2
50.6
self reported educational attainment
1
1
1
10.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil count
2
50.6
self reported educational attainment
1
10.2
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ras-related protein Rab-39A
469251
Macaque
RAB42, member RAS oncogene family
720282
Horse
RAB42, member RAS oncogene family
VGNC:50748
100070702
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ras-related protein Rab-39A
Macaque
RAB42, member RAS oncogene family
Horse
RAB42, member RAS oncogene family
Publication Statistics
PubMed Score 0.73
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title