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Tdark
MMGT1
Membrane magnesium transporter 1

Protein Summary
Description
Mediates Mg(2+) transport.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305963
  • ENSP00000306220
  • ENSG00000169446

Symbol
  • EMC5
  • TMEM32
  • EMC5
  • TMEM32
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.84
microRNA
0.79
histone modification site profile
0.76
kinase perturbation
0.71
virus perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.06   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.06   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
EMC4
Tbio
Novelty:  0.12174476
p_int:  0.999753587
p_ni:  0.000246413
Score:  0.995
Data Source:  BioPlex,STRINGDB
EMC8
Tdark
Novelty:  0.2452967
p_int:  0.999553264
p_ni:  0.000446736
Score:  0.992
Data Source:  BioPlex,STRINGDB
EMC9
Tdark
Novelty:  0.52441743
p_int:  0.998000058
p_ni:  0.00199994
p_wrong:  3e-9
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC3
Tbio
Novelty:  0.01113829
p_int:  0.994164752
p_ni:  0.005835243
p_wrong:  6e-9
Score:  0.994
Data Source:  BioPlex,STRINGDB
EMC10
Tbio
Novelty:  0.04986528
p_int:  0.990639876
p_ni:  0.009359988
p_wrong:  1.36e-7
Score:  0.994
Data Source:  BioPlex,STRINGDB
EMC6
Tbio
Novelty:  0.18299013
p_int:  0.986855518
p_ni:  0.010950335
p_wrong:  0.002194149
Score:  0.996
Data Source:  BioPlex,STRINGDB
EMC2
Tbio
Novelty:  0.05843267
p_int:  0.981564374
p_ni:  0.018435627
Score:  0.993
Data Source:  BioPlex,STRINGDB
EMC1
Tbio
Novelty:  0.05360812
p_int:  0.977783041
p_ni:  0.022216959
Score:  0.994
Data Source:  BioPlex,STRINGDB
EMC7
Tdark
Novelty:  0.28771768
p_int:  0.968036673
p_ni:  0.031963328
Score:  0.995
Data Source:  BioPlex,STRINGDB
UBQLN2
Tbio
Novelty:  0.00776132
Score:  0.888
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Miscellaneous transport and binding events (R-HSA-5223345)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Miscellaneous transport and binding events
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Miscellaneous transport and binding events
Transport of small molecules
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
50.6
childhood trauma measurement
1
1
1
26.6
1
1
0
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
50.6
childhood trauma measurement
1
26.6
0
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2384305
236792
Rat
RGD:1566339
302864
Horse
membrane magnesium transporter 1
VGNC:20222
100054769
Cow
membrane magnesium transporter 1
VGNC:31516
617557
Pig
membrane magnesium transporter 1
100520118
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
membrane magnesium transporter 1
Cow
membrane magnesium transporter 1
Pig
membrane magnesium transporter 1
Publication Statistics
PubMed Score 4.06
PubMed score by year
PubTator Score 1.39
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title