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Tbio
SLC44A3
Choline transporter-like protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000271227
  • ENSP00000271227
  • ENSG00000143036
  • ENST00000446120
  • ENSP00000389143
  • ENST00000467909
  • ENSP00000432789
  • ENST00000527077
  • ENSP00000433641
  • ENST00000529450
  • ENSP00000431836

Symbol
  • CTL3
  • CTL3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
virus perturbation
0.79
histone modification site profile
0.74
transcription factor binding site profile
0.66
PubMedID
0.63


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.3   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.3   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 44 member 3
VGNC:6126
469387
Macaque
solute carrier family 44 member 3
714768
Mouse
MGI:2384860
213603
Rat
RGD:1305808
295417
Dog
solute carrier family 44 member 3
VGNC:46419
490152
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 44 member 3
Macaque
solute carrier family 44 member 3
Mouse
Rat
Dog
solute carrier family 44 member 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N4M1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (10)
Glycerophospholipid biosynthesis (R-HSA-1483206)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Glycerophospholipid biosynthesis
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Phospholipid metabolism
Reactome
SLC-mediated transmembrane transport
Name
Explore in Pharos
Explore in Source
Glycerophospholipid biosynthesis
Metabolism
Metabolism of lipids
Phospholipid metabolism
SLC-mediated transmembrane transport
Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (15)
1 – 10 of 15
GDPD1
Tbio
Family: Enzyme
Novelty: 0.28722153
Score: 0.549
Data Source: STRINGDB
IMPA2
Tbio
Family: Enzyme
Novelty: 0.03983031
Score: 0.548
Data Source: STRINGDB
SLC5A7
Tchem
Family: Transporter
Novelty: 0.00232251
Score: 0.504
Data Source: STRINGDB
ERICH5
Tdark
Novelty: 5.57504212
Score: 0.474
Data Source: STRINGDB
THADA
Tbio
Novelty: 0.06983966
Score: 0.472
Data Source: STRINGDB
SEL1L3
Tdark
Novelty: 0.62775736
Score: 0.454
Data Source: STRINGDB
HUNK
Tchem
Family: Kinase
Novelty: 0.04316776
Score: 0.447
Data Source: STRINGDB
TMEM82
Tdark
Novelty: 2.5806762
Score: 0.441
Data Source: STRINGDB
PCYT1B
Tbio
Family: Enzyme
Novelty: 0.02972878
Score: 0.437
Data Source: STRINGDB
SLC39A2
Tbio
Family: Transporter
Novelty: 0.01886854
Score: 0.428
Data Source: STRINGDB
Publication Statistics
PubMed Score  8.30

PubMed score by year
PubTator Score  7.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer