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Tdark
TMEM151A
Transmembrane protein 151A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000327259
  • ENSP00000326244
  • ENSG00000179292

Symbol
  • TMEM151
  • TMEM151
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
kinase perturbation
0.6
tissue
0.59
cell line
0.58
transcription factor
0.57


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.17   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.17   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
2
3
78.7
BMI-adjusted waist circumference
1
3
3
73.9
BMI-adjusted hip circumference
2
2
3
68.1
insomnia measurement
1
2
0
1
67.5
self reported educational attainment
3
2
3
67.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
3
78.7
BMI-adjusted waist circumference
3
73.9
BMI-adjusted hip circumference
3
68.1
insomnia measurement
0
1
67.5
self reported educational attainment
3
67.4
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 151A
VGNC:976
466673
Macaque
transmembrane protein 151A [Source:HGNC Symbol;Acc:HGNC:28497]
Mouse
MGI:2147713
381199
Dog
transmembrane protein 151A
VGNC:47484
483713
Cow
transmembrane protein 151B
519699
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 151A
Macaque
transmembrane protein 151A [Source:HGNC Symbol;Acc:HGNC:28497]
Mouse
Dog
transmembrane protein 151A
Cow
transmembrane protein 151B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N4L1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (32)
1 – 10 of 32
SOWAHD
Tdark
Novelty:  6.91525424
Score:  0.689
Data Source:  STRINGDB
TMEM71
Tdark
Novelty:  1.54067166
Score:  0.621
Data Source:  STRINGDB
TMEM179
Tdark
Novelty:  2.21288966
Score:  0.596
Data Source:  STRINGDB
C1orf167
Tdark
Novelty:  1.10306407
Score:  0.585
Data Source:  STRINGDB
SAMD10
Tdark
Novelty:  2.02197004
Score:  0.585
Data Source:  STRINGDB
ANKDD1A
Tdark
Novelty:  1.522813
Score:  0.58
Data Source:  STRINGDB
DRC7
Tdark
Novelty:  0.40606004
Score:  0.543
Data Source:  STRINGDB
ZSCAN32
Tdark
Family:  TF
Novelty:  3.83392226
Score:  0.53
Data Source:  STRINGDB
C9orf64
Tdark
Novelty:  0.66704146
Score:  0.511
Data Source:  STRINGDB
TMEM88
Tbio
Novelty:  0.14612337
Score:  0.487
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.17

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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