Tdark SLC22A24 Solute carrier family 22 member 24

Protein Summary

Description

SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q8N4F4

Gene Name

• SLC22A24

Ensembl ID

• ENST00000326192
• ENSP00000321549
• ENSG00000197658

Symbol

• NET46

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
co-expressed gene	0.93
gene perturbation	0.81
cell line	0.63
tissue	0.45
chemical	0.44

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc22 Family Of Organic Cation And Anion Transporters / Orphan Or Poorly Characterized Slc22 Family Members / Solute Carrier Family 22 Member 24

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.69   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 61   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.69   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0