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Tdark
ZNF843
Zinc finger protein 843

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315678
  • ENSP00000322899
  • ENSG00000176723
  • ENST00000618063
  • ENSP00000483573
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.61
cell type or tissue
0.53
histone modification site profile
0.5
transcription factor
0.47
transcription factor binding site profile
0.43


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 126   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 126   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
3
0
1.2
84.4
Glycosuria
5
3
0
4.1
77.2
body mass index
1
1
1
70
1
1
0
1.3
48.5
red blood cell distribution width
4
1
4
47.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
84.4
Glycosuria
0
4.1
77.2
body mass index
1
70
0
1.3
48.5
red blood cell distribution width
4
47.7
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N446-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (5)
1 – 5 of 5
LIMD1
Tbio
Novelty:  0.04868333
p_int:  0.99888956
p_ni:  0.001110439
p_wrong:  1e-9
Score:  0.208
Data Source:  BioPlex,STRINGDB
CAMK2D
Tchem
Family:  Kinase
Novelty:  0.02326864
p_int:  0.971166129
p_ni:  0.028833871
Score:  0.305
Data Source:  BioPlex,STRINGDB
CAMK2B
Tchem
Family:  Kinase
Novelty:  0.00793595
p_int:  0.97099336
p_ni:  0.029006637
p_wrong:  3e-9
Score:  0.818
Data Source:  BioPlex,STRINGDB
PSMG3
Tchem
Novelty:  0.01730294
p_int:  0.918356866
p_ni:  0.081582038
p_wrong:  0.000061095
Score:  0.173
Data Source:  BioPlex,STRINGDB
GNAQ
Tbio
Novelty:  0.0008997
p_int:  0.804903492
p_ni:  0.167330821
p_wrong:  0.027765687
Score:  0.188
Data Source:  BioPlex,STRINGDB
Publication Statistics
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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