Tdark SLC25A45 Solute carrier family 25 member 45

Protein Summary

Description

SLC25A45 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q8N413
• Q6PL49
• Q8IW29

Gene Name

• SLC25A45

Ensembl ID

• ENST00000294187
• ENSP00000294187
• ENSG00000162241
• ENST00000398802
• ENSP00000381782
• ENST00000527174
• ENSP00000435489
• ENST00000534028
• ENSP00000431769

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.87
cell type or tissue	0.64
transcription factor perturbation	0.61
cellular component	0.56
transcription factor	0.56

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc25 Family Of Mitochondrial Transporters / Mitochondrial Amino Acid Transporter Subfamily / Solute Carrier Family 25 Member 45

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 35   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.81   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0