SLC25A45
Solute carrier family 25 member 45
Protein Summary
SLC25A45 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
- ENST00000294187
- ENSP00000294187
- ENSG00000162241
- ENST00000398802
- ENSP00000381782
- ENST00000527174
- ENSP00000435489
- ENST00000534028
- ENSP00000431769
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.87 | ||
cell type or tissue | 0.64 | ||
transcription factor perturbation | 0.61 | ||
cellular component | 0.56 | ||
transcription factor | 0.56 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.34 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 35 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.34 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 35 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (20)
1 – 10 of 20
FRMD8
Novelty: 0.39375892
Score: 0.791
Data Source: STRINGDB
FAM174A
Novelty: 0.30693139
Score: 0.759
Data Source: STRINGDB
SLC25A35
Family: Transporter
Novelty: 1.19834062
Score: 0.693
Data Source: STRINGDB
RNF186
Novelty: 0.15621021
Score: 0.568
Data Source: STRINGDB
TIGD3
Novelty: 1.23642174
Score: 0.561
Data Source: STRINGDB
ZNF785
Family: TF
Novelty: 0.42629766
Score: 0.543
Data Source: STRINGDB
KDM2A
Family: Epigenetic
Novelty: 0.01990727
Score: 0.536
Data Source: STRINGDB
SDHAF4
Family: Enzyme
Novelty: 0.24150488
Score: 0.529
Data Source: STRINGDB
FAM89B
Novelty: 0.10306021
Score: 0.527
Data Source: STRINGDB
LTBP3
Novelty: 0.0190763
Score: 0.492
Data Source: STRINGDB
Gene Ontology Terms (4)
Functions (1)
Components (2)
Processes (1)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Traits (13)
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
creatinine measurement | 2 | 2 | 3 | 88.9 | |||||
glomerular filtration rate | 1 | 2 | 2 | 88.5 | |||||
uric acid measurement | 1 | 1 | 1 | 78.9 | |||||
BMI-adjusted hip circumference | 2 | 6 | 6 | 77.9 | |||||
serum alanine aminotransferase measurement | 2 | 2 | 1 | 7.3 | 69.6 | ||||
Items per page:
1 – 5 of 13
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
creatinine measurement | 3 | 88.9 | |||||
glomerular filtration rate | 2 | 88.5 | |||||
uric acid measurement | 1 | 78.9 | |||||
BMI-adjusted hip circumference | 6 | 77.9 | |||||
serum alanine aminotransferase measurement | 1 | 7.3 | 69.6 | ||||
Find similar targets by:
UniProt Keyword
No Header | No Header | ||
|---|---|---|---|
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 25 member 45 | VGNC:7750 | 451322 | |||||
Macaque | solute carrier family 25 member 45 | 716427 | ||||||
Mouse | MGI:2147731 | 107375 | ||||||
Rat | RGD:1589953 | 689625 | ||||||
Dog | solute carrier family 25 member 45 | 483740 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | solute carrier family 25 member 45 | |||||
Macaque | solute carrier family 25 member 45 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 25 member 45 | |||||
Publication Statistics
PubMed Score 1.34
PubMed score by year
PubTator Score 0.92
PubTator score by year