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Tdark
C17orf53
Uncharacterized protein C17orf53

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000245382
  • ENSP00000245382
  • ENSG00000125319
  • ENST00000319977
  • ENSP00000313500
  • ENST00000585683
  • ENSP00000466618
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.41   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 183   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.41   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 183   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
SSSCA1
Tdark
Novelty:  0.53523038
p_int:  0.999661832
p_ni:  0.000010046
p_wrong:  0.000328122
Data Source:  BioPlex
MARS2
Tbio
Family:  Enzyme
Novelty:  0.02533315
p_int:  0.997688072
p_ni:  0.000722144
p_wrong:  0.001589784
Score:  0.325
Data Source:  BioPlex,STRINGDB
ZPR1
Tbio
Novelty:  0.01893839
p_int:  0.937393825
p_ni:  0.062599777
p_wrong:  0.000006398
Score:  0.269
Data Source:  BioPlex,STRINGDB
ZBTB40
Tbio
Family:  TF
Novelty:  0.17413605
Score:  0.65
Data Source:  STRINGDB
FAM210A
Tdark
Novelty:  0.2598101
Score:  0.641
Data Source:  STRINGDB
FAM199X
Tdark
Novelty:  1.32503264
Score:  0.641
Data Source:  STRINGDB
DCDC5
Tdark
Novelty:  0.21703566
Score:  0.588
Data Source:  STRINGDB
DCDC1
Tbio
Novelty:  0.21703566
Score:  0.588
Data Source:  STRINGDB
STARD3NL
Tbio
Novelty:  0.11798896
Score:  0.588
Data Source:  STRINGDB
CCDC170
Tbio
Novelty:  0.08078387
Score:  0.555
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (28)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
6
5
8
98.7
mean corpuscular volume
2
3
3
97.8
reticulocyte measurement
3
3
5
97.4
heel bone mineral density
3
3
6
96.8
mean reticulocyte volume
1
3
3
96.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
8
98.7
mean corpuscular volume
3
97.8
reticulocyte measurement
5
97.4
heel bone mineral density
6
96.8
mean reticulocyte volume
3
96.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 17 C17orf53 homolog
VGNC:10096
454722
Macaque
chromosome 16 open reading frame, human C17orf53
711524
Mouse
MGI:2387601
217216
Rat
RGD:1305385
303566
Dog
chromosome 9 C17orf53 homolog
VGNC:49206
607087
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 17 C17orf53 homolog
Macaque
chromosome 16 open reading frame, human C17orf53
Mouse
Rat
Dog
chromosome 9 C17orf53 homolog
Publication Statistics
PubMed Score 2.41
PubMed score by year
PubTator Score 0.38
PubTator score by year
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Related Publications
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PMID
Year
Title