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Tdark
ZNF786
Zinc finger protein 786

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000491431
  • ENSP00000417470
  • ENSG00000197362
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
gene perturbation
0.81
transcription factor binding site profile
0.66
protein domain
0.58
microRNA
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.02   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 121   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.02   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
1
1
23.2
sum of basophil and neutrophil counts
1
1
1
20.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
1
23.2
sum of basophil and neutrophil counts
1
20.1
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 786
VGNC:4584
472581
Macaque
zinc finger protein 786
709906
Mouse
MGI:3026883
330301
Rat
RGD:2293500
100158223
Dog
zinc finger protein 786
VGNC:48816
106557477
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 786
Macaque
zinc finger protein 786
Mouse
Rat
Dog
zinc finger protein 786
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N393-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (17)
1 – 10 of 17
NKTR
Tbio
Novelty: 0.01287691
p_int: 0.999864305
p_ni: 0.000135691
p_wrong: 4e-9
Score: 0.206
Data Source: BioPlex,STRINGDB
TOPORS
Tbio
Family: Enzyme
Novelty: 0.03910082
p_int: 0.999013643
p_ni: 0.000986333
p_wrong: 2.4e-8
Score: 0.204
Data Source: BioPlex,STRINGDB
GPALPP1
Tdark
Novelty: 13.22858591
p_int: 0.997622021
p_ni: 0.002377678
p_wrong: 3.01e-7
Score: 0.187
Data Source: BioPlex,STRINGDB
PCDHA13
Tdark
Novelty: 1.14537708
p_int: 0.989601964
p_ni: 0.010398015
p_wrong: 2.1e-8
Score: 0.365
Data Source: BioPlex,STRINGDB
NEMF
Tbio
Novelty: 0.05052246
p_int: 0.944740128
p_ni: 0.055259872
Score: 0.221
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
COQ10B
Tdark
Novelty: 0.59492584
Score: 0.731
Data Source: STRINGDB
EEF1E1
Tbio
Novelty: 0.06216577
Score: 0.641
Data Source: STRINGDB
CAMKMT
Tbio
Family: Enzyme
Novelty: 0.00382649
Score: 0.593
Data Source: STRINGDB
TBPL1
Tbio
Novelty: 0.02184575
Score: 0.558
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.02

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer