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Tbio
SLC35F6
Solute carrier family 35 member F6

Protein Summary
Description
Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000344420
  • ENSP00000345528
  • ENSG00000213699

Symbol
  • C2orf18
  • ANT2BP
  • TANGO9
  • C2orf18
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.8
tissue sample
0.7
small molecule perturbation
0.62
cell line
0.61
tissue
0.6


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.23   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.23   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F6
VGNC:10763
459085
Mouse
MGI:1922169
74919
Rat
RGD:1309228
298851
Dog
solute carrier family 35 member F6
VGNC:46380
483003
Horse
solute carrier family 35 member F6
VGNC:23177
100071319
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F6
Mouse
Rat
Dog
solute carrier family 35 member F6
Horse
solute carrier family 35 member F6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N357-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (10)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (43)
1 – 10 of 43
ORAI1
Tchem
Family: IC
Novelty: 0.00179685
p_int: 0.970875582
p_ni: 0.028962947
p_wrong: 0.000161471
Data Source: BioPlex
KLK15
Tbio
Family: Enzyme
Novelty: 0.00083978
p_int: 0.855197772
p_ni: 0.144786921
p_wrong: 0.000015307
Data Source: BioPlex
MGARP
Tbio
Novelty: 0.02883753
p_int: 0.767938045
p_ni: 0.157389415
p_wrong: 0.07467254
Data Source: BioPlex
OTUD4
Tbio
Novelty: 0.17121119
Score: 0.708
Data Source: STRINGDB
NUS1
Tbio
Family: Enzyme
Novelty: 0.02022029
Score: 0.703
Data Source: STRINGDB
LMBRD1
Tbio
Novelty: 0.02503332
Score: 0.681
Data Source: STRINGDB
NUDT3
Tbio
Family: Enzyme
Novelty: 0.06052313
Score: 0.656
Data Source: STRINGDB
SLC25A5
Tbio
Family: Transporter
Novelty: 0.00749909
Score: 0.645
Data Source: STRINGDB
UAP1L1
Tdark
Family: Enzyme
Novelty: 0.36065169
Score: 0.628
Data Source: STRINGDB
PITPNB
Tbio
Novelty: 0.03432693
Score: 0.628
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.23

PubMed score by year
PubTator Score  1.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer