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Tbio
ELMOD1
ELMO domain-containing protein 1

Protein Classes
Protein Summary
Description
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265840
  • ENSP00000265840
  • ENSG00000110675
  • ENST00000443271
  • ENSP00000412257
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.96
histone modification site profile
0.7
microRNA
0.65
tissue sample
0.64
transcription factor perturbation
0.54


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.94   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.94   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ELMO domain containing 1
VGNC:50374
451525
Macaque
ELMO domain containing 1
707026
Mouse
MGI:3583900
270162
Rat
RGD:1564186
315670
Dog
ELMO domain containing 1
VGNC:40312
489423
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ELMO domain containing 1
Macaque
ELMO domain containing 1
Mouse
Rat
Dog
ELMO domain containing 1
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (29)
1 – 10 of 29
TMED7
Tdark
Novelty: 0.31193294
p_int: 0.999150424
p_ni: 3e-9
p_wrong: 0.000849573
Data Source: BioPlex
LRRC15
Tbio
Novelty: 0.03701624
p_int: 0.941618291
p_ni: 0.058381704
p_wrong: 5e-9
Score: 0.169
Data Source: BioPlex,STRINGDB
LDHC
Tbio
Family: Enzyme
Novelty: 0.00213484
p_int: 0.915441499
p_ni: 0.078184395
p_wrong: 0.006374106
Score: 0.416
Data Source: BioPlex,STRINGDB
PKP3
Tbio
Novelty: 0.0269462
p_int: 0.830930804
p_ni: 0.166589745
p_wrong: 0.002479451
Score: 0.205
Data Source: BioPlex,STRINGDB
SLC12A9
Tdark
Family: Transporter
Novelty: 0.12936696
Score: 0.658
Data Source: STRINGDB
AKAP6
Tbio
Family: Enzyme
Novelty: 0.02961416
Score: 0.648
Data Source: STRINGDB
THG1L
Tbio
Family: Enzyme
Novelty: 0.17339179
Score: 0.644
Data Source: STRINGDB
KDELC2
Tdark
Novelty: 0.7820617
Score: 0.6
Data Source: STRINGDB
PASK
Tbio
Family: Kinase
Novelty: 0.14004084
Score: 0.592
Data Source: STRINGDB
ARL2
Tbio
Family: Enzyme
Novelty: 0.01989908
Score: 0.577
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.94

PubMed score by year
PubTator Score  1.37

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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