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Tdark
SVBP
Small vasohibin-binding protein

Protein Summary
Description
Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869). Also required to enhance the solubility and secretion of VASH1 and VASH2 (PubMed:20736312, PubMed:27879017).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372521
  • ENSP00000361599
  • ENSG00000177868
  • ENST00000372522
  • ENSP00000361600

Symbol
  • CCDC23
  • CCDC23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.11   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.11   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (7)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (8)
1 – 8 of 8
VASH1
Tbio
Novelty: 0.01008912
Score: 0.915
Data Source: STRINGDB
VASH2
Tbio
Novelty: 0.04406673
Score: 0.775
Data Source: STRINGDB
MS4A5
Tdark
Novelty: 0.875
Score: 0.714
Data Source: STRINGDB
BCS1L
Tbio
Family: Enzyme
Novelty: 0.00258512
Score: 0.675
Data Source: STRINGDB
SNX22
Tdark
Novelty: 0.61538462
Score: 0.59
Data Source: STRINGDB
ZNF628
Tdark
Family: TF
Novelty: 0.18545455
Score: 0.53
Data Source: STRINGDB
ERMAP
Tbio
Novelty: 0.05005478
Score: 0.493
Data Source: STRINGDB
RUNDC1
Tdark
Novelty: 1.55555556
Score: 0.474
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.11

PubMed score by year
PubTator Score  3.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer