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Tbio
SVBP
Small vasohibin-binding protein

Protein Summary
Description
Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869). Also required to enhance the solubility and secretion of VASH1 and VASH2 (PubMed:20736312, PubMed:27879017).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372521
  • ENSP00000361599
  • ENSG00000177868
  • ENST00000372522
  • ENSP00000361600

Symbol
  • CCDC23
  • CCDC23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (8)
VASH1
Tbio
Novelty:  0.01093552
Score:  0.915
Data Source:  STRINGDB
VASH2
Tbio
Novelty:  0.03882519
Score:  0.775
Data Source:  STRINGDB
MS4A5
Tdark
Novelty:  0.47356151
Score:  0.714
Data Source:  STRINGDB
BCS1L
Tbio
Family:  Enzyme
Novelty:  0.01764582
Score:  0.675
Data Source:  STRINGDB
SNX22
Tdark
Novelty:  0.26806147
Score:  0.59
Data Source:  STRINGDB
ZNF628
Tdark
Family:  TF
Novelty:  0.50407457
Score:  0.53
Data Source:  STRINGDB
ERMAP
Tbio
Novelty:  0.04270359
Score:  0.493
Data Source:  STRINGDB
RUNDC1
Tdark
Novelty:  1.23644681
Score:  0.474
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
1
1
1
50.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
1
50.6
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1916466
69216
Rat
RGD:1311232
362578
Dog
small vasohibin binding protein
VGNC:49865
100683368
Horse
small vasohibin binding protein
VGNC:23781
100053543
Cow
small vasohibin binding protein
VGNC:35497
614073
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
small vasohibin binding protein
Horse
small vasohibin binding protein
Cow
small vasohibin binding protein
Publication Statistics
PubMed Score 13.24
PubMed score by year
PubTator Score 3.17
PubTator score by year
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Related Publications
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PMID
Year
Title