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Tbio
SVBP
Small vasohibin-binding protein

Protein Summary
Description
Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146869). Also required to enhance the solubility and secretion of VASH1 and VASH2 (PubMed:20736312, PubMed:27879017).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372521
  • ENSP00000361599
  • ENSG00000177868
  • ENST00000372522
  • ENSP00000361600

Symbol
  • CCDC23
  • CCDC23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
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ARCHS4
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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.24   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1916466
69216
Rat
RGD:1311232
362578
Dog
small vasohibin binding protein
VGNC:49865
100683368
Horse
small vasohibin binding protein
VGNC:23781
100053543
Cow
small vasohibin binding protein
VGNC:35497
614073
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
small vasohibin binding protein
Horse
small vasohibin binding protein
Cow
small vasohibin binding protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N300-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (8)
1 – 8 of 8
VASH1
Tbio
Novelty: 0.01093552
Score: 0.915
Data Source: STRINGDB
VASH2
Tbio
Novelty: 0.03882519
Score: 0.775
Data Source: STRINGDB
MS4A5
Tdark
Novelty: 0.47356151
Score: 0.714
Data Source: STRINGDB
BCS1L
Tbio
Family: Enzyme
Novelty: 0.01764582
Score: 0.675
Data Source: STRINGDB
SNX22
Tdark
Novelty: 0.26806147
Score: 0.59
Data Source: STRINGDB
ZNF628
Tdark
Family: TF
Novelty: 0.50407457
Score: 0.53
Data Source: STRINGDB
ERMAP
Tbio
Novelty: 0.04270359
Score: 0.493
Data Source: STRINGDB
RUNDC1
Tdark
Novelty: 1.23644681
Score: 0.474
Data Source: STRINGDB
Publication Statistics
PubMed Score  13.24

PubMed score by year
PubTator Score  3.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer