Tbio SYS1 Protein SYS1 homolog

Protein Summary

Description

Involved in protein trafficking. May serve as a receptor for ARFRP1. SYS1 forms a complex with ADP-ribosylation factor-related protein ARFRP1 (MIM 604699) and targets ARFRP1 to the Golgi apparatus (Behnia et al., 2004 [PubMed 15077113]).[supplied by OMIM, Aug 2009]

Uniprot Accession IDs

• Q8N2H4
• C9JFB3
• E1P620
• Q5QPU7
• Q96SD8
• Q9BQZ2
• Q9BQZ4
• Q9H1F7

Gene Name

• SYS1

Ensembl ID

• ENST00000243918
• ENSP00000243918
• ENSG00000204070
• ENST00000372727
• ENSP00000361812
• ENST00000426004
• ENSP00000416506

Symbol

• C20orf169
• C20orf169
• dJ453C12.4
• dJ453C12.4.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor	0.8
transcription factor perturbation	0.8
tissue sample	0.71
transcription factor binding site profile	0.7
disease perturbation	0.68

Protein Classes

PANTHER Classes

Protein / Transporter / Protein Sys1 Homolog

Protein / Transfer/carrier Protein / Protein Sys1 Homolog

DTO Classes

Protein / Transporter / Protein Sys1 Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.5   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.5   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0