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Tdark
ZCCHC24
Zinc finger CCHC domain-containing protein 24

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372336
  • ENSP00000361411
  • ENSG00000165424

Symbol
  • C10orf56
  • Z3CXXC8
  • C10orf56
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
small molecule perturbation
0.75
microRNA
0.72
gene perturbation
0.67
virus perturbation
0.64


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.18   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.18   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (30)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
4
5
5
90.8
body height
6
4
6
90.7
3
3
0
1.1
90.4
BMI-adjusted hip circumference
2
6
6
87.7
lymphocyte percentage of leukocytes
2
2
2
85.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
5
90.8
body height
6
90.7
0
1.1
90.4
BMI-adjusted hip circumference
6
87.7
lymphocyte percentage of leukocytes
2
85.5
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCHC-type containing 24
VGNC:7866
450547
Macaque
zinc finger CCHC-type containing 24
702083
Mouse
MGI:1919168
71918
Rat
RGD:1306164
361104
Dog
zinc finger CCHC-type containing 24
VGNC:51997
610507
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCHC-type containing 24
Macaque
zinc finger CCHC-type containing 24
Mouse
Rat
Dog
zinc finger CCHC-type containing 24
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N2G6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (51)
1 – 10 of 51
CLIP3
Tbio
Novelty:  0.08151142
Score:  0.729
Data Source:  STRINGDB
SH3RF2
Tbio
Family:  Enzyme
Novelty:  0.14257663
Score:  0.701
Data Source:  STRINGDB
ARSJ
Tdark
Family:  Enzyme
Novelty:  0.00769596
Score:  0.685
Data Source:  STRINGDB
MMD2
Tbio
Novelty:  0.07096035
Score:  0.632
Data Source:  STRINGDB
SERGEF
Tdark
Novelty:  0.36520994
Score:  0.558
Data Source:  STRINGDB
APCDD1
Tbio
Novelty:  0.25122542
Score:  0.551
Data Source:  STRINGDB
RSPH1
Tbio
Novelty:  0.02982525
Score:  0.548
Data Source:  STRINGDB
TSTD2
Tdark
Family:  Enzyme
Novelty:  1.81982307
Score:  0.54
Data Source:  STRINGDB
C22orf42
Tdark
Novelty:  3.51429983
Score:  0.539
Data Source:  STRINGDB
ANKRD33B
Tdark
Novelty:  3.05956917
Score:  0.538
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.18

PubMed score by year
PubTator Score  0.43

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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