Tbio CFAP52 Cilia- and flagella-associated protein 52

Protein Summary

Description

May play a role in cell growth and/or survival. WD repeat-containing proteins, such as WDR16, play crucial roles in a wide range of physiologic functions, including signal transduction, RNA processing, remodeling the cytoskeleton, regulation of vesicular traffic, and cell division (Silva et al., 2005 [PubMed 15967112]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q8N1V2
• B2RDU7
• Q5DX23
• Q8TC73
• Q8TCI3

Gene Name

• CFAP52

Ensembl ID

• ENST00000352665
• ENSP00000339449
• ENSG00000166596
• ENST00000396219
• ENSP00000379521

Symbol

• WDR16
• WDRPUH
• WDR16
• WDRPUH

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.76
protein domain	0.73
transcription factor binding site profile	0.63
tissue sample	0.52
transcription factor	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 91   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0