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Tclin
CA13
Carbonic anhydrase 13

Protein Summary
Description
Reversible hydration of carbon dioxide. Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see MIM 114800.[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321764
  • ENSP00000318912
  • ENSG00000185015

Symbol
  • CAXIII
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
histone modification site profile
0.89
transcription factor perturbation
0.74
microRNA
0.64
PubMedID
0.6


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.02   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 180   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.02   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 180   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 130
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 9
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
carbonic anhydrase 13
VGNC:12000
747299
Mouse
MGI:1931322
71934
Rat
RGD:1560453
499566
Dog
carbonic anhydrase 13
VGNC:38608
487030
Horse
carbonic anhydrase 13 [Source:HGNC Symbol;Acc:HGNC:14914]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
carbonic anhydrase 13
Mouse
Rat
Dog
carbonic anhydrase 13
Horse
carbonic anhydrase 13 [Source:HGNC Symbol;Acc:HGNC:14914]
Protein Structure (15 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q8N1Q1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 15
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (4)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Reversible hydration of carbon dioxide
Name
Explore in Pharos
Explore in Source
Metabolism
Reversible hydration of carbon dioxide
Gene Ontology Terms (6)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (36)
1 – 10 of 36
CYP24A1
Tchem
Family: Enzyme
Novelty: 0.00107155
Score: 0.798
Data Source: STRINGDB
THRSP
Tbio
Novelty: 0.00938864
Score: 0.72
Data Source: STRINGDB
UHMK1
Tbio
Family: Kinase
Novelty: 0.04117277
Score: 0.677
Data Source: STRINGDB
SLC9A1
Tchem
Family: Transporter
Novelty: 0.00096678
Score: 0.61
Data Source: STRINGDB
PHF24
Tdark
Novelty: 0.60441071
Score: 0.592
Data Source: STRINGDB
SNRPB
Tbio
Novelty: 0.01503535
Score: 0.577
Data Source: STRINGDB
SLC9A3
Tclin
Family: Transporter
Novelty: 0.00146466
Score: 0.573
Data Source: STRINGDB
SLC4A4
Tbio
Family: Transporter
Novelty: 0.00352439
Score: 0.568
Data Source: STRINGDB
PURA
Tbio
Novelty: 0.00660312
Score: 0.558
Data Source: STRINGDB
TXNRD2
Tbio
Family: Enzyme
Novelty: 0.002052
Score: 0.544
Data Source: STRINGDB
Publication Statistics
PubMed Score  89.02

PubMed score by year
PubTator Score  45.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer