Tdark LRRC47 Leucine-rich repeat-containing protein 47

Protein Summary

Uniprot Accession IDs

• Q8N1G4
• Q9ULN5

Gene Name

• LRRC47

Ensembl ID

• ENST00000378251
• ENSP00000367498
• ENSG00000130764

Symbol

• KIAA1185

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.99
kinase perturbation	0.91
histone modification site profile	0.75
transcription factor binding site profile	0.66
tissue sample	0.61

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Leucine-rich Repeat-containing Protein 47

Protein / Ligase / Aminoacyl-trna Synthetase / Leucine-rich Repeat-containing Protein 47

DTO Classes

Protein / Enzyme / Ligase / Aminoacyl-trna Synthetase / Leucine-rich Repeat-containing Protein 47

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 25   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0