ORMDL3
ORM1-like protein 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.9 | ||
cellular component | 0.75 | ||
histone modification site profile | 0.69 | ||
tissue sample | 0.66 | ||
transcription factor | 0.66 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Neutrophil degranulation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Immune System | ||||
Innate Immune System | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Neutrophil degranulation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil count | 11 | 14 | 22 | 99.9 | |||||
leukocyte count | 11 | 14 | 28 | 99.8 | |||||
myeloid white cell count | 5 | 7 | 7 | 99.6 | |||||
childhood onset asthma | 4 | 6 | 0 | 1.3 | 99.3 | ||||
16 | 17 | 1 | 1.2 | 99.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil count | 22 | 99.9 | |||||
leukocyte count | 28 | 99.8 | |||||
myeloid white cell count | 7 | 99.6 | |||||
childhood onset asthma | 0 | 1.3 | 99.3 | ||||
1 | 1.2 | 99.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ORMDL sphingolipid biosynthesis regulator 3 | VGNC:9495 | 746120 | |||||
Macaque | ORMDL sphingolipid biosynthesis regulator 3 | 699154 | ||||||
Mouse | MGI:1913862 | 66612 | ||||||
Rat | RGD:1560577 | 360618 | ||||||
Dog | ORMDL sphingolipid biosynthesis regulator 3 | VGNC:44147 | 480530 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ORMDL sphingolipid biosynthesis regulator 3 | |||||
Macaque | ORMDL sphingolipid biosynthesis regulator 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ORMDL sphingolipid biosynthesis regulator 3 | |||||
PMID | Year | Title |
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