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Tdark
TMEM61
Transmembrane protein 61

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371268
  • ENSP00000360315
  • ENSG00000143001
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.54
virus perturbation
0.45
cell line
0.41
chemical
0.41
disease
0.41


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
19
28
44
9.8
100
total cholesterol measurement
12
23
30
14.5
99.9
apolipoprotein B measurement
2
12
13
99.9
HMG CoA reductase inhibitor use measurement
1
3
3
94.6
serum metabolite measurement
2
3
67
91.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
44
9.8
100
total cholesterol measurement
30
14.5
99.9
apolipoprotein B measurement
13
99.9
HMG CoA reductase inhibitor use measurement
3
94.6
serum metabolite measurement
67
91.3
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 61
717082
Rat
RGD:6501786
100909776
Dog
transmembrane protein 61
VGNC:47593
610503
Cow
transmembrane protein 61
VGNC:36101
615684
Pig
transmembrane protein 61
100628096
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 61
Rat
Dog
transmembrane protein 61
Cow
transmembrane protein 61
Pig
transmembrane protein 61
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N0U2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (16)
1 – 10 of 16
CD3EAP
Tbio
Family:  Enzyme
Novelty:  0.04978272
Score:  0.651
Data Source:  STRINGDB
DONSON
Tbio
Novelty:  0.05354868
Score:  0.601
Data Source:  STRINGDB
TMEM207
Tdark
Novelty:  0.35957705
Score:  0.56
Data Source:  STRINGDB
DYDC1
Tdark
Novelty:  0.35666983
Score:  0.559
Data Source:  STRINGDB
DYDC2
Tdark
Novelty:  1.40061645
Score:  0.557
Data Source:  STRINGDB
TMEM116
Tdark
Novelty:  1.81767497
Score:  0.538
Data Source:  STRINGDB
TMEM213
Tdark
Novelty:  0.87036241
Score:  0.531
Data Source:  STRINGDB
TEX264
Tbio
Novelty:  0.32406417
Score:  0.53
Data Source:  STRINGDB
TMEM72
Tdark
Novelty:  1.02661278
Score:  0.525
Data Source:  STRINGDB
SLC35G2
Tdark
Family:  Transporter
Novelty:  0.57896683
Score:  0.525
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.12

PubMed score by year
PubTator Score  0.18

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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