Tbio TCTE3 Tctex1 domain-containing protein 3

Protein Summary

Description

May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity).

Uniprot Accession IDs

• Q8IZS6

Gene Name

• TCTE3

Ensembl ID

• ENST00000366774
• ENSP00000355736
• ENSG00000184786
• ENST00000610291
• ENSP00000478684
• ENSG00000275368

Symbol

• TCTEX1D3
• TCTEX1D3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.83
transcription factor binding site profile	0.78
cell type or tissue	0.76
transcription factor perturbation	0.54
cellular component	0.5

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Tctex1 Domain-containing Protein 3

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Tctex1 Domain-containing Protein 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.4   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 24   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.4   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0