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Tdark
ADGRF2
Adhesion G-protein coupled receptor F2

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296862
  • ENSP00000296862
  • ENSG00000164393
  • ENST00000398742
  • ENSP00000381727
  • ENST00000467205
  • ENSP00000425269

Symbol
  • GPR111
  • PGR20
  • PGR20
  • GPR111
  • hGPCR35
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.63
disease
0.57
phenotype
0.54
cell line
0.52
chemical
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
GDB
Protein-Protein Interactions (21)
1 – 10 of 21
LRRC46
Tdark
Novelty: 1.159245
Score: 0.822
Data Source: STRINGDB
GPR141
Tdark
Family: GPCR
Novelty: 0.30711523
Score: 0.726
Data Source: STRINGDB
GPR139
Tchem
Family: GPCR
Novelty: 0.04083224
Score: 0.726
Data Source: STRINGDB
GPR148
Tbio
Family: GPCR
Novelty: 0.019374
Score: 0.697
Data Source: STRINGDB
ADGRA1
Tdark
Family: GPCR
Novelty: 0.24926468
Score: 0.691
Data Source: STRINGDB
ADGRA3
Tbio
Family: GPCR
Novelty: 0.06798451
Score: 0.668
Data Source: STRINGDB
MCCD1
Tdark
Novelty: 0.55621159
Score: 0.657
Data Source: STRINGDB
ADGRA2
Tbio
Family: GPCR
Novelty: 0.02854335
Score: 0.636
Data Source: STRINGDB
PPRC1
Tbio
Novelty: 0.00182088
Score: 0.58
Data Source: STRINGDB
PDZD7
Tbio
Novelty: 0.09467006
Score: 0.576
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.44

PubMed score by year
PubTator Score  1.88

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer