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Tdark
SLC22A15
Solute carrier family 22 member 15

Protein Summary
Description
Probably transports organic cations (By similarity). Appears not to be the agmatine transporter. Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369502
  • ENSP00000358514
  • ENSG00000163393
  • ENST00000369503
  • ENSP00000358515

Symbol
  • FLIPT1
  • FLIPT1
  • PRO34686
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
histone modification site profile
0.69
microRNA
0.55
PubMedID
0.53
tissue sample
0.52


Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.21   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 66   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.21   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 22 member 15
VGNC:6127
469426
Macaque
solute carrier family 22 member 15
710102
Mouse
MGI:3607704
242126
Rat
RGD:1311184
310732
Dog
solute carrier family 22 member 15
VGNC:46276
483136
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 22 member 15
Macaque
solute carrier family 22 member 15
Mouse
Rat
Dog
solute carrier family 22 member 15
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IZD6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Organic cation transport (R-HSA-549127)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Organic cation transport
Reactome
Organic cation/anion/zwitterion transport
Reactome
SLC-mediated transmembrane transport
Reactome
Transport of bile salts and organic acids, metal ions and amine compounds
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Organic cation transport
Organic cation/anion/zwitterion transport
SLC-mediated transmembrane transport
Transport of bile salts and organic acids, metal ions and amine compounds
Transport of small molecules
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (49)
1 – 10 of 49
ANKRD13C
Tbio
Novelty:  1.5309683
p_int:  0.999986677
p_ni:  0.000008306
p_wrong:  0.000005017
Data Source:  BioPlex
VAPA
Tbio
Novelty:  0.00169209
p_int:  0.999977975
p_ni:  0.000022025
Data Source:  BioPlex
ERGIC2
Tbio
Novelty:  0.08610944
p_int:  0.999830799
p_ni:  0.000169199
p_wrong:  2e-9
Data Source:  BioPlex
GHDC
Tbio
Novelty:  0.08423152
p_int:  0.999747748
p_ni:  0.000252252
Data Source:  BioPlex
VAPB
Tbio
Novelty:  0.00542377
p_int:  0.999555254
p_ni:  0.000444746
Data Source:  BioPlex
ZFPL1
Tbio
Novelty:  0.1829181
p_int:  0.998274541
p_ni:  0.001648662
p_wrong:  0.000076798
Data Source:  BioPlex
DPY19L4
Tdark
Family:  Enzyme
Novelty:  0.99997412
p_int:  0.98139111
p_ni:  0.018182299
p_wrong:  0.000426591
Data Source:  BioPlex
GUF1
Tbio
Novelty:  0.00422028
p_int:  0.975108235
p_ni:  0.024167658
p_wrong:  0.000724107
Data Source:  BioPlex
LMBRD2
Tdark
Novelty:  0.60495132
p_int:  0.962234967
p_ni:  0.034331621
p_wrong:  0.003433413
Data Source:  BioPlex
CNNM1
Tdark
Novelty:  0.11053515
p_int:  0.96086658
p_ni:  0.039131745
p_wrong:  0.000001675
Data Source:  BioPlex
Publication Statistics
PubMed Score  4.21

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer