You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RPUSD2
RNA pseudouridylate synthase domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315616
  • ENSP00000323288
  • ENSG00000166133
  • ENST00000559271
  • ENSP00000453036

Symbol
  • C15orf19
  • PUS9
  • C18B11
  • C15orf19
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.68
kinase perturbation
0.66
small molecule perturbation
0.65
cell type or tissue
0.63
cell line
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.55   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.55   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (65)
PFDN4
Tbio
Novelty:  0.02133605
p_int:  0.999999605
p_ni:  1.29e-7
p_wrong:  2.66e-7
Score:  0.159
Data Source:  BioPlex,STRINGDB
GPR156
Tdark
Family:  GPCR
Novelty:  0.39183023
p_int:  0.999999078
p_ni:  9.22e-7
Data Source:  BioPlex
CELA2B
Tdark
Family:  Enzyme
Novelty:  0.43122129
p_int:  0.999992739
p_ni:  0.00000726
Score:  0.228
Data Source:  BioPlex,STRINGDB
NEU4
Tchem
Family:  Enzyme
Novelty:  0.02621605
p_int:  0.999949834
p_ni:  0.000024145
p_wrong:  0.000026021
Score:  0.188
Data Source:  BioPlex,STRINGDB
PMPCA
Tbio
Family:  Enzyme
Novelty:  0.01842996
p_int:  0.999666927
p_ni:  0.000250225
p_wrong:  0.000082848
Score:  0.237
Data Source:  BioPlex,STRINGDB
ALDH8A1
Tbio
Family:  Enzyme
Novelty:  0.09598756
p_int:  0.999495913
p_ni:  0.000347355
p_wrong:  0.000156732
Score:  0.525
Data Source:  BioPlex,STRINGDB
SPATA8
Tdark
Novelty:  0.54146501
p_int:  0.897250943
p_ni:  0.000546481
p_wrong:  0.102202576
Score:  0.332
Data Source:  BioPlex,STRINGDB
SBDS
Tbio
Novelty:  0.00818779
Score:  0.864
Data Source:  STRINGDB
CUL3
Tbio
Novelty:  0.0028737
Score:  0.835
Data Source:  STRINGDB
DNAJC17
Tbio
Novelty:  0.42044015
Score:  0.799
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
2
2
79.2
waist-hip ratio
2
2
2
39.6
red blood cell distribution width
1
1
1
35
BMI-adjusted waist-hip ratio
1
1
1
31.4
mathematical ability
1
1
1
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
79.2
waist-hip ratio
2
39.6
red blood cell distribution width
1
35
BMI-adjusted waist-hip ratio
1
31.4
mathematical ability
1
28.1
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA pseudouridylate synthase domain containing 2
VGNC:1884
453337
Macaque
RNA pseudouridylate synthase domain containing 2
708166
Mouse
MGI:1918066
271842
Rat
RGD:6494740
100911166
Dog
RNA pseudouridylate synthase domain containing 2
VGNC:45752
487496
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA pseudouridylate synthase domain containing 2
Macaque
RNA pseudouridylate synthase domain containing 2
Mouse
Rat
Dog
RNA pseudouridylate synthase domain containing 2
Publication Statistics
PubMed Score 0.55
PubMed score by year
PubTator Score 0.14
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title