CHPF
Chondroitin sulfate synthase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.87 | ||
transcription factor binding site profile | 0.76 | ||
cellular component | 0.73 | ||
pathway | 0.68 | ||
virus perturbation | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chondroitin sulfate biosynthesis | ||||
Reactome | Chondroitin sulfate/dermatan sulfate metabolism | ||||
Reactome | Glycosaminoglycan metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of carbohydrates | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chondroitin sulfate biosynthesis | ||||
Chondroitin sulfate/dermatan sulfate metabolism | ||||
Glycosaminoglycan metabolism | ||||
Metabolism | ||||
Metabolism of carbohydrates | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 3 | 4 | 88.8 | |||||
creatinine measurement | 1 | 2 | 2 | 85.6 | |||||
electrocardiography | 1 | 1 | 60 | 68.6 | |||||
soluble triggering receptor expressed on myeloid cells 2 measurement | 1 | 1 | 0 | 15744.7 | 53.3 | ||||
vital capacity | 1 | 1 | 1 | 40.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 4 | 88.8 | |||||
creatinine measurement | 2 | 85.6 | |||||
electrocardiography | 60 | 68.6 | |||||
soluble triggering receptor expressed on myeloid cells 2 measurement | 0 | 15744.7 | 53.3 | ||||
vital capacity | 1 | 40.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | chondroitin polymerizing factor | VGNC:135 | 743513 | |||||
Macaque | chondroitin polymerizing factor | 703860 | ||||||
Mouse | MGI:106576 | 74241 | ||||||
Rat | RGD:1359458 | 316533 | ||||||
Horse | chondroitin polymerizing factor | VGNC:16515 | 100059511 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | chondroitin polymerizing factor | |||||
Macaque | chondroitin polymerizing factor | |||||
Mouse | ||||||
Rat | ||||||
Horse | chondroitin polymerizing factor | |||||
PMID | Year | Title |
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